HIV :: Human genome sciences reports positive results of ccr5 mab in hiv-1

Human Genome Sciences, Inc. (Nasdaq: HGSI) today announced that the results of a Phase 1 clinical trial of HGS004 (CCR5 mAb) demonstrate that it was well tolerated and exhibited antiviral activity in patients who are infected with HIV-1, the retrovirus that causes acquired immunodeficiency syndrome (AIDS). The results were reported in San Francisco in an oral presentation at the American Society for Microbiology’s 46th Annual Conference on Antimicrobial Agents and Chemotherapy (ICAAC).

Obesity :: Overweight in Early Childhood Increases Chances for Obesity at Age 12

Children who are overweight as toddlers or preschoolers are more likely to be overweight or obese in early adolescence, report researchers in a collaborative study by the NIH and several academic institutions. The researchers periodically collected height and weight measurements of a sample of children, beginning at age 2 and continuing until age 12. Their analysis, appearing in the September Pediatrics, provides some of the strongest evidence to date that overweight in early childhood increase the chances for overweight in later life.

Depression :: Drug Trial Shows Some Gains Against Major Depression

But the benefits were relatively small, indicating need for newer medications. Two different drug regimens for difficult-to-treat major depression — one a combination of two newer drugs and the other a single, older drug — were comparable in putting people with depression in remission.

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