Health :: Jefferson researchers find nanoparticle shows promise in reducing radiation side effects

With the help of tiny, transparent zebrafish embryos, researchers are hoping to prove that a microscopic nanoparticle can be part of a “new class of radioprotective agents” that help protect normal tissue from radiation damage just as well as standard drugs. They’ve shown that the nanoparticle, DF-1 — a soccer ball-shaped, hollow, carbon-based structure known as a fullerene — is as good as two antioxidant drugs and FDA-approved Amifostine in fending off radiation damage from normal tissue.

Gene :: Gene linked with mental illness shapes brain region

A gene variant associated with mental illness goes hand-in-hand with enlargement of a brain region that handles negative emotions, researchers at UT Southwestern Medical Center and the Central Texas Veterans Health Care System have found.

Stem Cell :: Plan to create human-cow embryos

Scientists from King’s submitted a licence application yesterday (6 November) to the Human Fertilisation and Embryology Authority (HFEA) to allow them to fuse human cells with animal eggs. If granted, the licence will boost research into some of the most debilitating and untreatable neurological diseases.

Breast Cancer :: Younger african-american women are at higher risk

Despite an overall decline in invasive breast cancer in the United States in recent years, African-American women, particularly younger ones, have not seen a significant decline in their rates, according to researchers at the University of Pittsburgh. These findings, which are being presented at the American Public Health Association (AHPA) Annual Meeting in Boston, Nov. 4 ? 8, strongly suggest the need for additional research to understand why these differences persist and to determine whether avoidable or preventable factors account for these puzzling patterns, according to the investigators.

Health :: Economist shows good fences do make good neighbors

A new study led by a UC Irvine economist debunks a popular argument against urban sprawl — that living farther from neighbors decreases social interaction. In fact, the data shows that suburban living is better for one’s social life.

HIV :: An AIDS-related virus tricks cells to become tumors, new Penn study finds

Researchers at the University of Pennsylvania School of Medicine have discovered how the Kaposi’s sarcoma-associated herpesvirus (KSHV) subverts a normal cell process in order to promote tumor growth. The finding, published in the most recent issue of PLoS Pathogens, offers new potential strategies for treating Kaposi’s sarcoma and other cancers associated with viruses

Diabetes :: Enzyme may hold key to new treatment of diabetic kidney disease

Northwestern University researchers have found an enzyme, called “ACE2,” may hold the potential to treat diabetic kidney disease, the most common form of kidney disease.The researchers have found low levels of the ACE2 enzyme in kidneys of diabetic mice. When ACE2 was further decreased with an inhibitor drug, kidney disease worsened. Studies are now needed using compounds that increase the level of ACE2 in the kidneys of diabetic mice to see if it reverses or prevents kidney disease.

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