RNA :: Mechanism for the in-vivo transport of siRNA

RNA interference, a natural mechanism that inhibits the gene expression of individual genes in eukaryotic cells, is a major topic in modern biology. However, their potential was usable to only a limited extent in mammals because the mechanism for the uptake of small RNAs was unknown up to now. ETH Zurich biologists have now clarified this, which also opens the door for therapies based on this mechanism.

Healthcare :: GPS-like technology helps pinpoint best methods for moving injured players

The 15 minutes it took to remove Buffalo Bills player Kevin Everett off the field after he suffered a spinal cord injury may seem like a long time for someone needing acute medical care, but in fact, those minutes underscore how critical it is to carefully move a player with a suspected spinal cord injury off the field. It also highlights the challenges faced when needing to minimize any further movement to an injured spinal cord.

Pain :: Rating your pain from 0 to 10 might not help your doctor

The most commonly used measure for pain screening may only be modestly accurate, according to researchers from the Indiana University School of Medicine and the University of North Carolina. In a study that appears in the October issue of the Journal of General Internal Medicine, they evaluate the usefulness of a scale that asks patients in primary care to rate their current pain from 0 (no pain) to 10 (worst pain).

Bone :: Bone-growing nanomaterial could improve orthopaedic implants

For orthopaedic implants to be successful, bone must meld to the metal that these artificial hips, knees and shoulders are made of. A team of Brown University engineers, led by Thomas Webster, has discovered a new material that could significantly increase this success rate.

Prostate Cancer :: University of Minnesota study refutes belief that black men have more aggressive prostate cancer

A University of Minnesota study of prostate cancer tumors from Caucasian and African-American men has shown no evidence that the cancer is more aggressive in black men. Lead investigator Akhouri Sinha, a professor of genetics, cell biology, and development and research scientist at the Minneapolis VA Medical Center, said the belief that black men’s tumors are more aggressive is based on studies that failed to match patients properly and used only indirect means to measure tumor aggressiveness.

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