Arthritis :: Bone erosion reduced by denosumab in phase 2 trial

Treatment with denosumab 60 mg and 180 mg, with background methotrexate, reduces the progression of bone erosion according to results of a 227 patient-Phase II trial presented today at EULAR 2007, the Annual European Congress of Rheumatology in Barcelona, Spain.

Rheumatoid Arthritis :: Increased alcohol intake associated with decreased risk of developing rheumatoid arthritis

New data presented today at EULAR 2007, the Annual European Congress of Rheumatology in Barcelona, Spain, suggests that alcohol may protect against rheumatoid arthritis, with three units a week exhibiting protective effects and ten units a week being more protective still. An alcohol consumption of three units per week or more also reduced the risk by smoking or by a genetic predisposition to RA.

Infectious Disease :: Infectious diseases experts issue blueprint to avert

New vaccines are available to make significant gains against cervical cancer deaths and debilitating pain from shingles, but infectious diseases experts warn that their full potential will not be realized without changes in the way vaccines for adults and adolescents are promoted, financed and delivered in the United States.

Vitamin A :: A potential role for retinoic acid in autoimmune and inflammatory diseases

An important finding, which could eventually lead to a new therapeutic approach for treating autoimmune and inflammatory diseases such as rheumatoid arthritis, colitis, psoriasis and others, was announced today by researchers at the La Jolla Institute for Allergy & Immunology. The studies, conducted in laboratory mice, demonstrated the role of retinoic acid, a substance derived when vitamin A is broken down in the body, in regulating inflammation.

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