Hypertension :: Combination for Blood Pressure Control in hypertensive patients

A multicenter study of a pill that combines two drugs for hypertension shows significant benefit for people with hard-to-control high blood pressure. The study, conducted at the University of Maryland School of Medicine and 118 other sites, was focused on bringing down systolic blood pressure, the top number in a blood pressure reading, which is the more difficult number to bring down.

Cholesterol :: Role of cholesterol in atheromatous disease

In conditions with elevated concentrations of LDL particles, especially small LDL particles, cholesterol promotes atheroma plaque deposits in the walls of arteries, a condition known as atherosclerosis, which is a major contributor to coronary heart disease and other forms of cardiovascular disease.

Influenza :: Promise Against H5N1 Influenza Virus

Experiments in mice show that an antiviral drug currently used against annual influenza strains also can suppress the deadly influenza virus that has spread from birds to humans, killing dozens of people in Vietnam, Cambodia and Thailand since early 2004. This study, the first published report conducted on oseltamivir against the H5N1 influenza strain circulating in Vietnam, found that the drug, sold commercially as Tamiflu, dramatically boosted the survival rate of infected mice.

HIV :: HIV Therapy Greatly Extends Life of Key T Cells

Interleukin-2 (IL-2), an immune-boosting drug used experimentally in HIV therapy, greatly increases the lifespan of certain subsets of immune system T cells in some HIV-positive people who respond to this therapy, discovered researchers from the National Institutes of Health (NIH) Clinical Center and the National Institute of Allergy and Infectious Diseases (NIAID), part of the NIH. A report describing the study, led by the Clinical Center?s Joseph A. Kovacs, M.D., appears online today in The Journal of Clinical Investigation.

Williams Syndrome :: New Clues About Brain Function in Human Behavior

Researchers at the National Institute of Mental Health (NIMH), part of the National Institutes of Health, have discovered a genetically controlled brain mechanism responsible for social behavior in humans – one of the most important but least understood aspects of human nature. The findings are reported in Nature Neuroscience, published online on July 10, 2005.

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