Cancer :: Can cancer drugs combine forces?
Individuals with chronic myeloid leukemia (CML) are treated first with a drug known as imatinib (Gleevec), which targets the protein known to cause the cancer (BCR-ABL).
Psychology :: Humans mispredict their emotions after decision making
Behavioral research over the past 15 years has confirmed what anyone who has purchased a house or dumped a significant other could tell you: When people make decisions, they anticipate that they may regret their choices.
Warfarin :: FDA approves updated Warfarin (Coumadin) prescribing information
The U.S. Food and Drug Administration announced the approval of updated labeling for the widely used blood-thinning drug, Coumadin, to explain that people’s genetic makeup may influence how they respond to the drug.
Pollution :: Air pollution linked to cardiovascular risk indices in healthy young adults
Researchers in Taiwan have demonstrated for the first time that urban air pollution simultaneously affects key indicators of cardiovascular risk in young adults: inflammation, oxidative stress, coagulation and autonomic dysfunction.
Pollution :: High pollution linked to poor lung function growth in children in Mexico City
Children who are chronically exposed to higher levels of air pollution show marked deficiencies in lung growth and function, and not just short-term breathing problems, according to researchers in Mexico.
COPD :: Ambulatory oxygen rarely a benefit in COPD patients without resting hypoxemia
Prescribing ambulatory oxygen in patients with chronic obstructive pulmonary disease improves exercise performance, but not the quality of their daily life unless they have resting hypoxemia, according to researchers in Toronto.
Neurology :: Researchers identify proteins involved in new neurodegenerative syndrome
The interplay of two proteins that bind to messenger RNA, a molecule that mediates translation of the information encoded in genes into proteins, triggers the appearance of fragile X-associated tremor/ataxia syndrome, a late-life disorder associated with the gene that causes fragile X syndrome in children, said researchers from Baylor College of Medicine in Houston and Emory University School of Medicine in a report that appears today in the journal Neuron.
Lupus :: Preclinical study suggests organ-transplant drug may aid in lupus fight
A compound related to a drug used in humans to prevent organ-transplant rejection attacks a key biochemical process in the faulty immune cells of lupus-prone mice, suggesting a possible new approach to combating the disease, UT Southwestern Medical Center researchers have found.
RNA :: Scientists link fragile X tremor/ataxia syndrome to binding protein in RNA
Scientists have discovered a key protein in the toxic brain pathway that leads to fragile X tremor/ataxia syndrome, an inherited neurodegenerative disorder. The finding, in a Drosophila (fly) model of FXTAS, could help unravel the complex mechanisms of FXTAS and lead scientists to develop therapies to target the protein.
Diabetes :: Gender, coupled with diabetes, affects vascular disease development
A team of researchers has determined that the vascular activities in diabetic animals vary according to sex. This discovery may eventually have implications for the way males and females are treated medically in the future.