Stem Cell :: U-M researchers dispute widely held ideas about stem cells

How do adult stem cells protect themselves from accumulating genetic mutations that can lead to cancer? For more than three decades, many scientists have argued that the “immortal strand hypothesis” – which states that adult stem cells segregate their DNA in a non-random manner during cell division — explains it. And several recent reports have presented evidence backing the idea.

Rheumatoid Arthritis :: Biologic treatment for rheumatoid arthritis and the risk of cancer

Findings of various clinical trials and observational studies conflict over the risk of malignancy related to the use of tumor necrosis factor alpha blockers. The relationship between rheumatoid arthritis (RA), an autoimmune disease marked by chronic inflammation of the joints and tissue surrounding vital organs, and the incidence of cancer is complicated.

Antibiotic :: Researchers discover new strategies for antibiotic resistance

With infections increasingly resistant to even the most modern antibiotics, researchers at the Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (LA BioMed) report in the September issue of Nature Reviews Microbiology on new clues they have uncovered in immune system molecules that defend against infection.

Smoking :: Smoking turns on genes permanently

Smoking tobacco is no longer considered sexy, but it may prove a permanent turn on for some genes. Research published today in the online open access journal BMC Genomics could help explain why former smokers are still more susceptible to lung cancer than those who have never smoked.

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