Hypertension :: Results of TROPHY study on hypertension are misleading

There may be as many as 70 million Americans with prehypertension. If these people can be treated pharmacologically to avoid or delay progression to clinical hypertension, there would be significant benefits to them and the overall health of the population. The recent TROPHY study seems to lead to that conclusion. However, two editorials published in the November issue of the American Journal of Hypertension emphatically argue that the study is flawed and the conclusions reached are misleading.

Face Transplant :: On the Ethics of Facial Transplant Research

Transplantation continues to push the frontiers of medicine into domains that summon forth troublesome ethical questions. Looming on the frontier today is human facial transplantation. “We develop criteria that, we maintain, must be satisfied in order to ethically undertake this as-yet-untried transplant procedure. We draw on the criteria advanced by Dr. Francis Moore in the late 1980s for introducing innovative procedures in transplant surgery”, Osborne P. Wiggins et al.

Face Transplant :: UK face transplant at Royal Free

The UK face transplantation team has been given permission to perform a series of full face transplant operations at the Royal Free Hospital in North London. The independent research ethics committee for the Royal Free delivered its decision to team leader, plastic and reconstruction surgeon, Mr Peter Butler, who said he was delighted with the news.

Health :: No link between juice and children’s weight

Drinking a glass of 100 percent fruit juice has long been thought of as a healthy habit for both adults and children. Recently, however, people have been confused about juice — how much to drink, how much to serve their children — partly because of the natural sweet taste of fruit juice.

Tuberculosis :: Drug Resistant Tuberculosis an emerging threat

Strains of tuberculosis (TB) that are resistant to both first-line and second-line drugs could threaten the success of not only tuberculosis programs, but also HIV treatment programs worldwide, according to an article published online this week in The Lancet. The report details a study by a team of investigators from the United States and South Africa, who found that highly resistant strains of TB were more common than previously thought in a rural area of KwaZulu Natal, South Africa, and were associated with high death rates in patients with HIV infection. TB accounts for approximately 1.7 million deaths worldwide, each year, and is the leading cause of death in HIV-infected patients in low-income countries.

ADHD :: Lisdexamfetamine dimesylate in ADHD phase 3 data presented

Shire plc (LSE: SHP, NASDAQ: SHPGY, TSX: SHQ) and its collaborative partner New River Pharmaceuticals Inc. (NASDAQ: NRPH) announced today that their investigational ADHD treatment, lisdexamfetamine dimesylate (also known as NRP104 or LDX), yielded a 60 percent improvement in the primary rating scale scores for symptoms of Attention-Deficit/Hyperactivity Disorder (ADHD) in children aged 6 to 12 years who received six months of treatment in an open-label phase III study. Results also demonstrated that at 6 months, 95 percent of children taking lisdexamfetamine dimesylate (NRP104/LDX) produced a “much improved” or “very much improved” rating on the Clinical Global Impressions ? Improvement score. These results were presented last weekend at a national meeting of child and adolescent psychiatrists.

Psychiatry :: Cognitive decline is often undetected

Many patients over the age of 65 who are hospitalized with an acute illness experience a subtle change in their cognitive ability that often goes undiagnosed, untreated and underreported. As a result, a patient’s ability to make decisions about his or her medical treatment may be negatively impacted.

ADHD :: Many adults with psychiatric disorders may also have undiagnosed ADHD

Shire plc (LSE: SHP, NASDAQ: SHPGY, TSX: SHQ) announced today that many adults with a depressive disorder, Bipolar Disorder (BPD), or an anxiety disorder may also have undiagnosed Attention-Deficit/Hyperactivity Disorder (ADHD), according to a longitudinal retrospective medical claims analysis presented today at a major medical meeting of child and adolescent psychiatrists.

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