Eyes :: Bayer & Regeneron’s VEGF Trap for the treatment of eye diseases, AMD

Bayer HealthCare (NYSE: BAY) and Regeneron Pharmaceuticals, Inc. (Nasdaq: REGN) today announced that the companies have entered into a collaboration agreement for the global development, and commercialization outside the U.S., of the VEGF Trap for the treatment of eye disease by local administration (VEGF Trap-Eye). The VEGF Trap-Eye, currently in Phase I and Phase II clinical trials, is a protein that binds to or ?traps? vascular endothelial growth factor (VEGF) and blocks its activity. VEGF is thought to play a critical role in certain eye diseases.

Asthma :: Asthma and soot from diesel trucks in bronx linked

Soot particles spewing from the exhaust of diesel trucks constitute a major contributor to the alarmingly high rates of asthma symptoms among school-aged children in the South Bronx, according to the results of a five-year study by researchers at New York University’s School of Medicine and Robert F. Wagner Graduate School of Public Service.

HIV :: Virco introduces an improved rapid methodology to establish new hiv-1 resistance profiles

Responding to the need to make timely evaluations and decisions when treating treatment experienced HIV patients, Virco (http://www.vircolab.com), a leader in drug resistance testing recently introduced an improved virco(R)TYPE HIV-1 test that rapidly determines the complex phenotypic resistance profiles for darunavir, tipranavir and other antiretroviral (ARV) drugs. Utilizing clinical trial data that was used to support the approval of darunavir and tipranavir, virco(R)TYPE HIV-1 reports now include Clinical Cut-Offs (CCOs) for these recently introduced agents(1). Virco(R)TYPE HIV-1 analyzes patient HIV-1 resistant genotypes using Virco’s large database to quickly and accurately predict phenotypic resistance. This timely determination of phenotypic resistance assists physicians in choosing a drug treatment plan that has the least amount of drug resistance.

Health :: New mechanism found that may underlie neuropathic pain

Researchers at Johnson & Johnson Pharmaceutical Research & Development (J&JPRD) announced on 15 October 2006 that they have discovered a new molecular mechanism that may underlie neuropathic pain. The clearer understanding of the root-cause of chronic neuropathic pain, and the preclinical validation of new targets for pharmaceutical therapies shown in this research, together present an opportunity for the development of new ways to treat the severe pain associated with such common conditions or diseases as sciatica, diabetic neuropathy and shingles.

Cancer :: Berkeley cancer genome center to study tumor genomics

The newly established Berkeley Cancer Genome Center, led by members of the Life Sciences Division in the Department of Energy’s Lawrence Berkeley National Laboratory, is one of seven Cancer Genome Characterization Centers to receive awards from the National Cancer Institute and the National Human Genome Research Institute. Earlier today the two institutes, both part of the National Institutes of Health, announced a three-year, $35 million project which will seek to identify important genetic changes involved in lung, brain, and ovarian cancers through genome analysis.

Pilates :: Top Six Benefits of Pilates Exercises

Pilates is the exercise of choice for dancers, gymnasts, and a host of famous Hollywood celebrities, and now it finds itself firmly entrenched in the mainstream. So why is pilates so hot? Pilates incredible popularity can be traced to the fact that it provides its faithful practitioners with benefits that you simply can’t get through traditional aerobics/strength training format.

Brain Tumor :: Children’s hospital Boston neurosurgeons to perform brain tumor removal during live webcast

On Wednesday, Oct. 25, at 1:00 p.m. EDT, neurosurgeons at Children’s Hospital Boston will remove a brain tumor employing functional mapping of the cortex on a 13-year-old pediatric patient during a live Webcast. Children’s hosts three to four Webcasts annually to showcase its pioneering care and technology to specialists and referring physicians around the world, and to educate consumers on the latest and most innovative medical treatments available.

Cancer :: Methoxyamine – new cancer therapy reverses resistance to chemotherapy

Case Western Reserve University’s Technology Transfer Office has entered a worldwide exclusive licensing agreement with TRACON Pharmaceuticals of San Diego, Calif., to develop Methoxyamine, a new cancer therapeutic that reverses cancer cell resistance to chemotherapy. Methoxyamine is a “first in class” drug that targets a specific DNA repair pathway.

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