Rheumatoid Arthritis :: Enbrel first biologic with up to 9 years rheumatoid arthritis safety

Amgen (NASDAQ: AMGN) announced Enbrel (R) (etanercept) is the first biologic with published data to show sustained improvements in multiple efficacy measures in rheumatoid arthritis patients completing up to nine years of therapy. Current data suggest Enbrel is both effective and safe in long-term RA use, and the new data, presented at the American College of Rheumatology scientific meeting, provide a degree of reassurance that unexpected safety concerns do not appear to develop after nine years of use.

ACTOS (pioglitazone HCl) halted progression of atherosclerosis as indicated by CIMT

Researchers today presented data showing that ACTOS (pioglitazone HCl) halted the progression of atherosclerosis as measured by carotid intima-media thickness (CIMT) in patients with type 2 diabetes. Results from the clinical trial, CHICAGO (Carotid intima-media thickness in Atherosclerosis using pioglitazone), are part of a late-breaker presentation at the American Heart Association’s Scientific Sessions 2006, coincidentally being held in Chicago, and coincide with an early online issue of the Journal of the American Medical Association.

Pourqui? lab identifies genes involved in formation of vertebral precursors

Mary Lee Dequeant, Ph.D., a Predoctoral Researcher at the Stowers Institute for Medical Research, and Olivier Pourqui?, Ph.D., Stowers Institute Investigator and an investigator with the Howard Hughes Medical Institute, are the first and last authors, respectively, on a paper that identifies a network of cyclic genes that shed light on the molecular basis of spine formation in the embryo.

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