Roche announced today that a large, international Phase III study (NO16967) of 627 previously treated patients with advanced colorectal cancer met its primary endpoint of progression-free survival.
GlaxoSmithKline (GSK) today announced additional results from an international Phase II short-term, six-week study of its investigational non-peptide oral platelet growth factor, eltrombopag. Analysis of data from this study showed that eltrombopag at 50mg or 75mg, resulted in a positive trend in decrease in bleeding incidence (all grades) in adult patients with chronic idiopathic thrombocytopenic purpura (ITP), an autoimmune condition which results in low blood platelet counts and bleeding from the small blood vessels. These data were presented today at the 48th Annual American Society of Hematology (ASH) meeting in Orlando, Florida.
A multicenter study on treating common ear infections in children with ear tubes adds to a growing body of evidence that favors antibiotic ear drops over antibiotics swallowed in pill or liquid form in such cases, a UT Southwestern Medical Center researcher reports.
The Food and Drug Administration is continuing its investigation of an outbreak of E. coli O157:H7 infections linked to eating food from Taco Bell restaurants in 5 states. FDA is collaborating with state and local health officials, the U.S. Centers for Disease Control and Prevention (CDC), and the firm to identify the cause of the outbreak.
The Food and Drug Administration (FDA) today ordered firms to stop marketing unapproved drug products containing quinine, a drug used to treat malaria, citing serious safety concerns, including deaths, associated with quinine products. There are multiple unapproved products containing quinine currently marketed. However, there is only one quinine product approved by the FDA.
SEER-Medicare analysis finds older men with early prostate cancer who were treated lived longer than those who were not treated. Study published in Dec. 13th issue of JAMA.
Microneedle-based vaccination with the current anthrax vaccine produced an equally effective immune response to intramuscular injection in rabbits using smaller dosage say researcher from Maryland and North Carolina. They report their findings in the December 2006 issue of the journal Infection and Immunity.
At the American Society of Hematology meeting in Orlando AkaRx, Inc. presented the positive results from two Phase I studies of AKR-501, an investigational compound for the treatment of thrombocytopenia.
Both men and women with schizophrenia are significantly more likely to have one or more of 46 common chronic health conditions than individuals without mental illness, according to study led by Caroline Carney Doebbeling, M.D., of the Indiana University School of Medicine and the Regenstrief Institute, Inc.
How does an organism know when it must produce a protein and in what amount? Clever control mechanisms are responsible for the regulation of protein biosynthesis. One such type of mechanism, discovered only a few years ago, is riboswitches, which function as a sort of “off” switch for the production of certain proteins.