Health :: FDA issues approvable letter for Entereg for POI

GlaxoSmithKline (NYSE: GSK) and Adolor Corporation (Nasdaq: ADLR) announced that the Food and Drug Administration (FDA) has issued a letter stating that the new drug application (NDA) for Entereg (alvimopan 12mg) for the management of post operative ileus (POI) is approvable. The FDA has requested 12-month safety data, including analysis of serious cardiovascular events, from study 014 (767905/014), an ongoing safety study in opioid-induced bowel dysfunction (OBD). The FDA also requested a risk management plan as part of the submission.

Health :: Toddlers learn complex actions from picture book reading

Parents who engage in the age-old tradition of picture-book reading are not only encouraging early reading development in their children but are also teaching their toddlers about the world around them, according to a study in the November issue of Developmental Psychology, published by the American Psychological Association (APA). This finding shows that interactions with life-like color pictures can aid in children?s learning.

Nutrition :: Dried plums act as antioxidant in some meats

To help satisfy consumer demand for more natural food products, researchers at Texas A&M University are investigating dried plums as a meat preservative. They are finding that dried plums, when pureed, have a good antioxidant capacity.

Health :: Hormone therapy does not improve quality of life for women

A postmenopausal hormone therapy trial conducted in Estonia indicates that hormone therapy does not improve women’s quality of life. The group receiving hormones and the comparison group showed no differences in general quality of life. Only those women that experienced hot flashes and night-time sweating reported beneficial effects.

Health :: Under 18s spell out what they need to enjoy quality of life on a ventilator

The growing number of children relying on portable home ventilators to breathe create their own ventilator-dependent lifestyles. But low esteem and social exclusion remain major problems. Professor Jane Noyes’ six-year study included interviews with over 100 children and parents. A third of the home ventilated children had received spinal or head injuries. The other two-thirds had congenital conditions.

Dementia :: New study shows increased risk of dementia before death

As the number of older people increases, the number of people who experience dementia before they die is also likely to increase, according to a new study. The research, spearheaded by Professor Carol Brayne at the University of Cambridge, has shown that factors believed to protect against dementia at earlier stages in life may not provide protection from dementia at the end of life.

Baby Care :: Active euthenasia for disabled infants?

The Royal College of Obstetricians and Gynaecology has raised an issue to debate over euthanasia for severely disabled newborn infants. The call was made in a submission to an ethical inquiry into increased survival rates of disabled children.

Lung Cancer :: The Medical Minute – A new tool for lung cancer diagnosis

This week’s New England Journal of Medicine reported that annual chest computed tomography (CT) scans on those at risk for lung cancer can detect it earlier, at a more treatable stage. In the study, more than 31,000 people in the United States and overseas underwent spiral CT scans of their chests at the beginning and again in seven to 18 months unless something was detected on the first scan.

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