Insulin :: Urocortin 3 gene important for the secretion of insulin

Knocking out the gene for a peptide associated with insulin secretion protects mice against the harmful effects of a high-fat diet, report researchers at the Salk Institute for Biological Studies. Their findings, detailed in the Proceedings of the National Academy of Sciences, suggest that urocortin 3, a new peptide recently discovered in the insulin secreting cells of the pancreas, plays a role in the increased production of insulin in response to high caloric intake in animals.

Insulin :: Stress-signaling fat is a culprit behind insulin resistance

A new study in the March issue of the journal Cell Metabolism, published by Cell Press, has identified a common link between multiple assaults on the body, including saturated fats, obesity, and certain types of drugs, all of which can lead to insulin resistance. The researchers found that these metabolic stresses lead to an upswing in production of a particular kind of fat molecule, known as ceramide.

Aging :: How eating less might make you live longer

Caloric restriction in non-obese people translates into less oxidative damage in muscle cells, according to a new study by Anthony Civitarese, Eric Ravussin and colleagues (Pennington Biomedical Research Center). As oxidative damage has been linked to aging, this could explain how limiting calorie intake without malnutrition extends life span.

Insulin :: Insulin dose errors can result when blood glucose meters are miscoded

When persons with diabetes use miscoded blood glucose meters to determine how much insulin to take, significant errors in insulin dose can result that may potentially lead to short- and long-term health complications, according to findings of a new study just published in the Journal of Diabetes Science and Technology.

Pregnancy :: Deakin University researcher unveils pregnancy mystery

A Deakin University study has unlocked one of the many mysteries of pregnancy — how the trace element copper is transported across the placenta. The findings provide a lead to the possible cause, treatment and prevention of a number of potentially fatal conditions.

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