Liver :: Insulin resistance and resolution of diabetes mellitus in non-alcoholic fatty liver disease

Diabetic patients with NAFLD are at risk for progressive liver disease. In this study, researchers examined connections between white adipose tissue (WAT, white fat) in the abdomen and medical disorders including insulin resistance (IR, inadequate response to insulin) and diabetes mellitus (DM, a metabolic disorder characterized by high blood sugar) in patients with obesity and NAFLD to evaluate whether cell signaling pathway profiles within WAT are associated with the presence of IR and whether they can predict the resolution of DM after weight loss.

Diabetes :: Decoding protein structures helps illuminate cause of diabetes

Any photographer can vouch for the difficulty of capturing a clear picture of a moving target. When it comes to molecules, however, sometimes the motion is exactly what scientists want to see – for example, to understand the pathological protein mis-folding and assembly that seem to underlie a host of human disorders, including diabetes and Alzheimer’s disease.

Insulin :: Insulin therapy shown to treat early experimental diabetic retinopathy

Researchers will present study results that indicate that subconjunctivally delivered insulin ameliorates degenerative and inflammatory responses in diabetic rat retinas at the Association for Research in Vision and Ophthalmology 2007 Annual Meeting in Fort Lauderdale, Fla. The presentation will take place on Thursday, May 10 from 10:45 a.m. to 12:30 p.m. in Hall B/C of the Greater Fort Lauderdale/Broward County Convention Center.

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