HIV :: Scientists unveil piece of HIV protein that may be key to AIDS vaccine development

In a finding that could have profound implications for AIDS vaccine design, researchers led by a team at the NIAID have generated an atomic-level picture of a key portion of an HIV surface protein as it looks when bound to an infection-fighting antibody. Unlike much of the constantly mutating virus, this protein component is stable and — more importantly, say the researchers — appears vulnerable to attack from this specific antibody, known as b12, that can broadly neutralize HIV.

HIV :: Migration played key role in HIV spread in South Africa

South Africa has one of the world?s highest rates of HIV infection. New research, led by Brown University professor Mark Lurie, shows that the movement of workers between urban and rural areas played a key role in the spread of the epidemic. Results are published in AIDS.

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