Flu :: Predicting danger of flu pandemic rests on differences in affected population

In the study, ?Simple Models of Influenza Progression Within a Heterogeneous Population,? Dr. Richard C. Larson, a former president of INFORMS and a professor at MIT, discusses the importance of forecasting and ultimately limiting the spread of disease while taking into account the different infection rates among those who might contract the disease.

Genome :: New Leishmania genome sequences highlight gene targets for treatment development

A comparison of three parasite species that cause Leishmaniasis has identified a small number of genes, many new to biology, that will provide a framework to target the search for new treatments. Leishmaniasis is a devastating disease that affects about two million people each year and threatens one-fifth of the world’s population and new treatments are desperately needed.

Rheumatoid Arthritis :: Roche’s Actemra improves rheumatoid arthritis symptoms

Results of the Option (TOcilizumab Pivotal Trial in Methotrexate Inadequate respONders) trial, the first multinational Phase III study outside of Japan, showed that patients treated with Actemra (either 4mg/kg or 8mg/kg) plus methotrexate achieved a significant and clinically important improvement in the signs and symptoms of moderate to severe rheumatoid arthritis (RA) compared to patients treated with placebo and methotrexate, a current standard of care.

Lyme Disease :: CDC Reports High Lyme Disease Rates in 10 States

Reported cases of Lyme disease have more than doubled since 1991, when Lyme became a nationally notifiable disease, according to a report by the Centers for Disease Control and Prevention (CDC). The report also said 93 percent of reported cases were concentrated in 10 states.

Meningitis :: Hot on the TRAIL of controlling inflammation in bacterial meningitis

In a study appearing online on June 14 in advance of publication in the July print issue of the Journal of Clinical Investigation, researchers at Charit?-Universit?tsmedizin Berlin report that the molecule known as TRAIL can limit excessive immune responses in bacterial meningitis, and as such may be of use to control inflammation of the spinal cord and brain, which causes brain cell death in this life-threatening disease.

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