Mice given a relatively new cancer drug can survive an otherwise lethal dose of vaccinia virus, a relative of smallpox virus, report scientists supported by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.
A promising new drug candidate that may be effective against both actively dividing and slow-growing Mycobacterium tuberculosis (M. tb) has begun testing in humans, the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, announced today. The novel antibiotic, PA-824, may shorten the time needed to treat tuberculosis (TB), a contagious disease that claims approximately two million lives worldwide each year. In partnership with the non-profit New York-based Global Alliance for TB Drug Development (TB Alliance), NIAID contributed to the drug candidate?s preclinical safety and efficacy testing in animal models. Now, a clinical trial to assess PA-824?s safety, sponsored by the TB Alliance, has opened at a medical clinic in Lincoln, NE.
New research on a bacterium that can survive encounters with specific immune system cells has strengthened scientists? belief that these plentiful white blood cells, known as neutrophils, dictate whether our immune system will permit or prevent bacterial infections. A paper describing the research was released today online in The Journal of Immunology. Frank R. DeLeo, Ph.D., of Rocky Mountain Laboratories (RML), part of the National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health, directed the work at RML, in Hamilton, MT, in collaboration with lead author Dori L. Borjesson, D.V.M., Ph.D., of the University of Minnesota in St. Paul.
Research performed at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, has revealed that oxygen therapy aimed at helping mice with acute lung inflammation breathe paradoxically worsened their illness. The researchers say excess oxygen appears to thwart a natural process that limits lung tissue damage. They overcame this deleterious side effect, however, by adding an inhaled anti-inflammatory drug to the oxygen therapy.
Ulcerative colitis is a common inflammatory disease of the colon that causes bloody diarrhea and heightens the risk of colon cancer. Ingesting the eggs of Trichuris suis, an intestinal worm, appears to be a safe and effective treatment for active ulcerative colitis, new research shows.
The obesity paradox lives on: Overweight and obese patients with multivessel coronary artery disease seem to fare better after coronary artery bypass surgery than their normal-weight counterparts, the results of a new study indicate.
The Food and Drug Administration (FDA) issued a public health advisory to inform patients and health care providers about the suspended marketing of Tysabri (nataluzimab) while the agency and the manufacturer evaluate two serious adverse events reported with its use.
An experimental treatment that harnesses the immune system to attack tumors can extend the lives of men fighting advanced prostate cancer, according to a study released, marking the first time a cancer vaccine has been shown to improve survival for any malignancy.
A vaccine that could prevent young women from developing most cases of cervical cancer could be on the market within a few years.
A healthy diet is very important for the development of good health during the early years of life. A faulty lifestyle and especially faulty food can lead to an unhealthy adult and therefore an unhealthy society and nation.