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Pancreatic Cancer :: Cytokeratin 20 Expression Linked to Poor Survival

According to an early on-line article published in the journal Cancer, strong expression of the protein cytokeratin 20 in pancreatic cancer is associated with significantly worse survival than low levels or no expression of cytokeratin 20. Patients diagnosed with pancreatic cancer who have a strong cytokeratin 20 expression may wish to undergo more aggressive therapy or participate in a clinical trial to improve their outcomes.

Osteosarcoma :: Osteosarcoma of the Distal End of the Femur

A retrospective multi-institutional study of 227 patients with osteosarcoma of the distal end of the femur was done to compare rates of local recurrence, metastasis, and survival.

Lymphoma :: Response to Glucocorticoids Predicts Survival with CNS Lymphoma

Patients with primary central nervous system (CNS) lymphoma who respond to initial treatment with glucocorticoids appear to have substantially better survival than patients who do not respond. These results were published in the journal Cancer.

Lung Cancer :: Pleural Lavage Cytology Helps Predict Outcomes in lung cancer

According to a recent article published in the Annals of Thoracic Surgery, pleural lavage cytology is significantly associated with survival outcomes in patients with non-small cell lung cancer and should be incorporated into the staging of the disease.

Osteosarcoma :: Zoledronic acid reduces Osteosarcoma lung metastases

Treatment with zoledronic acid can reduce lung metastases and improve survival in mice inoculated with an osteosarcoma cell line, according to a report in the December 22nd issue of Cancer.

Ovarian Cancer :: Surgeon tendency affects surgical outcomes in Ovarian Cancer

According to a recent article published in Gynecologic Oncology, a surgeon?s tendency to perform aggressive surgery greatly affects the rate of optimal surgery in patients with ovarian cancer.

Lymphoma :: BiovaxID – Promising for Follicular Lymphoma

According to results recently presented at the 47th annual meeting of the American Society of Hematology (ASH), the vaccine BiovaxID, which is still in clinical trials, appears very promising in the treatment of follicular lymphoma.

Ovarian Cancer :: Color Doppler Prior to Surgery Highly Accurate

According to a recent article published in the International Journal of Gynecology and Obstetrics, the addition of color Doppler imaging (CDI) to standard sonography greatly improves the accuracy of distinguishing between cancerous and non-cancerous ovarian masses prior to surgery.

Breast Cancer :: Optimal Radiation Therapy Improves Breast Cancer Survival

Among breast cancer patients who have undergone mastectomy, adjuvant radiation therapy improves survival. However, there is only a survival benefit when the dose is appropriate and the target area is sufficient. These results were published in the Journal of the National Cancer Institute.

Leukemia :: GX15-070 Active in Refractory CLL

According to results recently presented at the 47th annual meeting of the American Society of Hematology (ASH), the agent GX15-070, which is still in clinical trials, has anticancer activity in patients with chronic lymphocytic leukemia (CLL) who have stopped responding to standard therapies including chemotherapy, Rituxan?, and Campath?.