Researchers studying learning disabilities associated with neurofibromatosis type 1, or NF1, have traced the problem to excessive activity of a crucial signaling molecule and have successfully reversed the disabilities in mice by giving them an experimental drug. The findings provide hope that these learning problems may one day be treatable in humans.
In a study Steven Kossard, FACD; Ian Hamann, FACD; Barbara Wilkinson, BSc, concluded that urticarial dermatitis may represent a useful term for a subset of a reaction pattern designated most commonly as dermal hypersensitivity by pathologists. The term is not commonly used, and requires definition to determine whether it is clinically relevant.
Urticarial dermatitis seems to be a useful histological and clinical term for a subset of the dermal hypersensitivity reaction pattern.
The source of the name “lupus” is unclear. All explanations originate with the characteristic butterfly-shaped malar rash that the disease classically exhibits across the nose and cheeks.
Ichthyosis vulgaris is a common inherited skin disorder causing dry, scaly skin.
Genelabs Technologies Inc. said the U.S. Food and Drug Administration has asked for additional Phase III clinical trial of its experimental lupus drug Prestara.
Impetigo is a skin disorder caused by bacterial infection and characterized by crusting skin lesions. It is a superficial skin infection most common among children age 2-6 years (rare among people not in this age group).
A small study has shown that the osteoporosis drug raloxifene, sold as Evista, helps maintain bone mineral density (BMD) in menopausal women with systemic lupus erythematosus (SLE) who are on corticosteroids.
Sj?gren’s syndrome is an inflammatory disease that can affect many different parts of the body, but most often affects the tear and saliva glands. Patients with this condition may notice irritation, a gritty feeling, or painful burning in the eyes.
Lupus is caused by Natural Killer (NK) CD4– and CD8– T-Lymphocytes, also called T cells. These T cells multiply using a potassium gene channel. These same cells cause Diabetes.