Lymphoma :: Berlex Oncology Evaluating Combination Therapy for Non-Hodgkin’s Lymphoma

Berlex Oncology, a business unit of Berlex Laboratories, a U.S. affiliate of Schering AG, Germany (FSE: SCH; NYSE: SHR), today announced that a national clinical study is underway investigating a new approach to treating follicular B-cell lymphoma, a sub-type of non-Hodgkin?s lymphoma (NHL). NHL is the fifth most common form of cancer in the United States, with more than 56,000 new cases diagnosed each year. Follicular B-cell lymphoma is an indolent, or slow-growing, type of NHL that comprises approximately 30% of all diagnosed cases.

Hepatitis :: Glaxo eltrombopag improved platelet count in hepatitis C patients with thrombocytopenia

GlaxoSmithKline plc [NYSE:GSK, LSE:GSK] announced results from a global Phase II study of eltrombopag, an investigational non-peptide oral platelet growth factor. In this study of 74 hepatitis C patients with thrombocytopenia, (a condition where the blood has low platelet levels) more than 95% (p< 0.001) of patients treated with the highest dose of eltrombopag (75mg) had increased platelet counts. In addition, 71% - 91% of patients in all treatment groups were able to initiate antiviral therapy with pegylated interferon-α (IFN) and ribavirin, and 65% were able to be maintained on therapy.1 Full results from this Phase II study are being presented today at the 57th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD) in Boston, Massachusetts.

Cholesterol :: Pfizer’s torcetrapib/atorvastatin clinical trials – raising good cholesterol HDL

Pfizer Inc provided an update on the preliminary results of its torcetrapib/atorvastatin clinical trials in connection with the release of an American Heart Association abstract of a Phase 3 study in patients with heterozygous familial hypercholesterolemia (HeFH) that shows the drug significantly raising ‘good’ (HDL) cholesterol (56 percent) and additionally lowering ‘bad’ (LDL) cholesterol (27 percent) versus patients taking atorvastatin alone.

Multiple Sclerosis :: Alarming trend shows women face higher risk for MS

The number of women being diagnosed with multiple sclerosis in Canada is growing faster than the incidence among men, say researchers who suspect an environmental link. Multiple sclerosis (abbreviated MS, also known as disseminated sclerosis) is a chronic, inflammatory disease that affects the central nervous system (CNS).

Baby Care :: Defective serotonin pathways in the brainstem may increase infants’ vulnerability – SIDS

New autopsy data provide the strongest evidence yet that sudden infant death syndrome (SIDS) is not a “mystery” disease but has a concrete biological basis. In the November 1 issue of JAMA, researchers at Children’s Hospital Boston document abnormalities in the brainstem — a part of the brain that regulates breathing, blood pressure, body heat, and arousal — in babies who died from SIDS. The term cot death is often used in the United Kingdom, and crib death in North America.

OCD :: Children needed for imaging study of Obsessive-compulsive disorder

Children between the ages of 10 and 17 years are needed to participate in a research study of obsessive-compulsive disorder (OCD) at the University of Pittsburgh. The study will use Magnetic Resonance Imaging (MRI) to attempt to identify which areas of the brain are active when responding to certain stimuli.

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