Diabetes :: ACTOS is associated with a 38 percent lower risk of heart attack

New research, including two studies presented this week at the 43rd Annual Meeting of the European Association for the Study of Diabetes (EASD), further support the cardiovascular safety of ACTOS (pioglitazone HCI) and its benefits regarding improved blood glucose and blood lipid levels for patients with type 2 diabetes.

Diabetes :: Novartis’ Galvus efficacious in treating patients with type 2 diabetes

Uncontrolled patients with type 2 diabetes treated with metformin, one of the most prescribed oral medicines for this disease, were four times more likely to achieve recommended blood sugar control levels by adding Galvus® (vildagliptin) to their treatment compared to those who added a placebo, according to new clinical data[1].

Diabetes :: JAMA articles do not confirm difference in safety of Avandia and Actos, says GSK

GlaxoSmithKline (NYSE: GSK) believes that conclusions drawn from the most recent meta-analyses published by Drs. Nissen et. al. and Furberg et. al. in the Journal of the American Medical Association (JAMA) do not confirm a difference in the safety profile of Avandia (rosiglitazone) and Actos (pioglitazone).

Diabetes :: NDEP campaign highlights link between diabetes & cardiovascular disease

More than 20 million adults in the United States are living with diabetes and are at increased risk of cardiovascular disease (CVD). But there are steps that they can take to reduce the complications associated with these two diseases.

Diabetes :: Long-term use of diabetes drug increases heart attack risk by more than 40 percent

An analysis of four studies involving more than 14,000 patients found that long-term use of the diabetes drug rosiglitazone (Avandia) increased the risk of heart attack by 42 percent and doubled the risk of heart failure, according to a new report from researchers at Wake Forest University School of Medicine and colleagues. There was no effect on death from cardiovascular causes.

Diabetes :: Takeda statement on ACTOS meta-analysis published in the Journal of the American Medical Association

Takeda Pharmaceuticals North America, Inc. is aware of the review of ACTOS (pioglitazone HCl) data conducted by A. Michael Lincoff, M.D., and colleagues at the Cleveland Clinic, published in the Journal of the American Medical Association, which concluded that ACTOS is associated with a significantly lower risk of heart attack, stroke or death among a diverse population of 16,390 patients with diabetes versus control therapy.

Diabetes :: Mutations in the insulin gene can cause neonatal diabetes

Mutations in the insulin gene can cause permanent neonatal diabetes, an unusual form of diabetes that affects very young children and results in lifelong dependence on insulin injections, report researchers from the University of Chicago and Peninsula University (Exeter, UK) in Sept. 18, 2007, issue of the Proceedings of the National Academy of Sciences, published early online.