Prostate Cancer :: Detection of Early Prostate Cancer

A new study, using a unique detection method, has led scientists to identify several genes whose rearrangements in prostate cancer cells may play a role in the development and progression of the disease. Researchers at the University of Michigan, Ann Arbor, report that two genes, ETV1 and ERG, which previously were implicated as cancer-causing gene rearrangements in Ewing’s sarcoma (a relatively rare bone cancer), are now seen as important cancer-causing genes in prostate cancer. Closer analysis showed how rearrangement of these genes was responsible for their cancer-causing potential. The research appears in the October 28, 2005, issue of Science and was supported by the National Cancer Institute (NCI), part of the National Institutes of Health.