Prostate Cancer :: Scientists design a PSA-activated protoxin that kills prostate cancer

Scientists have found a way of using a protein made by prostate cancer to target and kill the cancer cells themselves. In preliminary studies the new therapy affected only the prostate, without causing damage to other healthy tissues, and now it is being tested in a phase I clinical trial, according to research presented at the 18th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics in Prague on Friday.

Cancer :: Firefighters face increased risk for certain cancers

University of Cincinnati (UC) environmental health researchers have determined that firefighters are significantly more likely to develop four different types of cancer than workers in other fields. Their findings suggest that the protective equipment firefighters have used in the past didn’t do a good job in protecting them against cancer-causing agents they encounter in their profession, the researchers say.

Cancer :: Growth factor signals influence balance between normal growth and cancerous growth – USA

Too much of a signaling protein called insulin-like growth factor-I (IGF-I) may fan the flames of cancer, while too little of the protein may cause short stature, dementia and osteoporosis. New research investigates how the growth hormone/IGF system is affected by the important tumor suppressor gene p53. This interplay of two signaling pathways reinforces questions about the long-term risks of prescribing growth hormone, while suggesting a future new avenue for cancer therapy.

Cancer :: Blocking stomach acid doesn’t raise cancer risk

Overall, the use of drugs that reduce stomach acid, such as H2 blockers and proton pump inhibitors, do not increase the risk of cancer of the esophagus or stomach, but it is informed that cancer risk is probably due to underlying conditions.

Prostate Cancer :: Largest PSA Bounce Study Eases Worry of Prostate Cancer Returning

Prostate cancer patients who have a temporary rise in their prostate specific antigen (PSA) levels after radiation therapy – called a PSA bounce – are not at an increased risk of their cancer coming back any more than those who don?t have a temporary rise, according to the largest study of its kind presented November 8, 2006, at the American Society for Therapeutic Radiology and Oncology?s 48th Annual Meeting in Philadelphia.

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