Prostate Cancer :: Baseline characteristics and predictors of progression of prostate cancer
Active surveillance with delayed intervention is a viable option for well-selected patients with favorable risk prostate cancer.
Active surveillance with delayed intervention is a viable option for well-selected patients with favorable risk prostate cancer.
Pathological stage and surgical margins are important predictors of prostate cancer recurrence after radical prostatectomy.
Almost all advanced cancers could be found early by intense screening of at-risk patients, according to researchers from New York and Malmo, Sweden who analyzed samples taken from a population-based cohort of 21,277 men in Malmo, Sweden between 1974 and 1986 to determine whether initial PSA plasma levels correlated with future diagnosis of advanced disease.
Veterans exposed to Agent Orange have a 48 percent increased risk of prostate cancer recurrence following surgery than their unexposed peers, and when the disease comes back, it seems more aggressive, researchers say.
In men with PSA relapse following prostatectomy, androgen deprivation is commonly used to slow tumor progression.
There are many questions surrounding watchful waiting/active surveillance as an initial treatment for prostate cancer and whether outcomes vary from patients who elect a more aggressive treatment sooner after diagnosis.
A nanocomposite particle can be constructed so that it has a mix of properties that would not otherwise happen in nature. By combining an organic matrix with metallic clusters that can absorb light, it is possible to incorporate such particles into cells and then destroy those targeted cells with a laser.
The use of targeted nanoparticles offers promising techniques for cancer treatment. Researchers in the laboratory of Mark E. Davis at the California Institute of Technology have been using small interfering RNA (siRNA), sometimes known as silencing RNA, to “silence” specific genes that are implicated in certain malignancies.
Northwestern University researchers have discovered that a recently identified genetic marker for prostate cancer is linked to a highly aggressive form of the disease.
Recent studies have indicated that the protein known as TRPM8 plays an important role in prostate cancer: high levels of TRPM8 have been found in prostate carcinoma compared to normal prostate epithelial cells, and TRPM8 has been suggested as a specific marker and therapeutic target in prostate cancer.