Patients with inoperable non-small cell lung cancer who receive an initial high dose of chemotherapy before their treatment begins can expect an increase in overall survival, according to a study in the July 1 issue of the International Journal of Radiation Oncology, Biology, Physics, the official journal of ASTRO.
Oregon Health & Science University Cancer Instituteresearchers have developed a Web-based software program that can helphead and neck cancer patients better predict their survivability.
Treatment with intravenous bisphosphonates — drugs used to reduce harm done to bones by cancer or cancer therapy — increases the risk of jaw or facial bone disease or infection, a large-scale comparative study by researchers at the University of Texas Medical Branch at Galveston (UTMB) has found.
Researchers at UT Southwestern Medical Center have determined how a substance derived from the bark of the South American lapacho tree kills certain kinds of cancer cells, findings that also suggest a novel treatment for the most common type of lung cancer.
Levels of a small non-coding RNA molecule called let-7 appear to define different stages of cancer better than some of the “classical” markers for tumor progression, researchers from the University of Chicago report in the June 25, 2007, early online edition of the Proceedings of the National Academy of Sciences.
New adjuvant treatments for breast cancer are cost-effective at improving survival, according to two new studies. Published in the August 1, 2007 issue of CANCER, a peer-reviewed journal of the American Cancer Society, the two studies looked at the cost-effectiveness of different drugs for the management of adjuvant therapies for early breast cancer.
A novel method of drug delivery to inhibit the growth of prostate cancer cells has been developed by a doctoral candidate in pharmacy at the Hebrew University of Jerusalem.
Research led by scientists at Weill Cornell Medical College has uncovered two new potential points of vulnerability on a key cancer-promoting protein, called XIAP. Drugs that target either of these activities could help push cancer cells back into a more regular programmed cell death and thereby reduce or eliminate tumors.
It may not seem so at the time, but women who suffer through morning sickness during their pregnancies actually may be fortunate. Those women may have a 30 percent lower risk of developing breast cancer later in life than mothers-to-be who experience nine nausea-free months, a new study by epidemiologists at the University at Buffalo suggests.
The cell labels the proteins it wants to dispose with Ubiquitin (Ub). Malfunctions in the ubiquitin-proteasome system can be fatal for the organism, resulting in cancer and immunological disorders. The knowledge about the ubiquitination reaction has led to the development of highly promising drugs. Biochemists at the University of Frankfurt now describe a novel Ub conjugation reaction that might allow a more efficient manipulation of key proteins in the treatment of cancer and other diseases.