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Osteosarcoma :: IDM Pharma’s Mepact, mifamurtide – Junovan in the Treatment of Osteosarcoma

IDM Pharma (NASDAQ:IDMI) announced today that the company has submitted a Marketing Authorization Application (MAA) in eCTD format (electronic common technical document) to the European Medicines Agency (EMEA) for Mepact (mifamurtide for injection), requesting approval for its use in the treatment of patients with newly diagnosed resectable high-grade osteosarcoma following surgical resection in combination with post-operative multi-agent chemotherapy. This announcement follows the October 25, 2006 submission of a New Drug Application (NDA) for Junovan (mifamurtide for injection) to the Food and Drug Administration (FDA) in the United States.

Health :: Caution issued on medicinal product

The Department of Health has warned consumers not to buy a medicinal product called Shenxiaotoutongsan as it contains three undeclared Western drug ingredients that may cause side effects.

Dengue Fever :: Woman ill with Dengue fever – Hong Kong

The Centre for Health Protection is investigating a Dengue fever case involving a 34-year-old woman who fell ill after returning from Malaysia.

Kidney Stone :: Drug prescribed for migraines and seizures increases risk of kidney stones

Topiramate (Topamax), a drug commonly prescribed to treat seizures and migraine headaches, can increase the propensity of calcium phosphate kidney stones, researchers at UT Southwestern Medical Center have found.

Hepatitis :: Bristol-Myers Squibb’s Baraclude, entecavir suppressed viral load to undetectable levels

Bristol-Myers Squibb Company (NYSE: BMY) announced data from a three-year cohort (ETV-022/901, n=119), which showed BARACLUDE? (entecavir) suppressed viral load to undetectable levels in 90 percent of nucleoside-na?ve chronic hepatitis B e-antigen (HBeAg) positive patients at week 144 who continued on-treatment from week 96. In this cohort, undetectable HBV DNA levels were defined as less than 300 copies per mL of blood as measured by polymerase chain reaction (PCR). Suppression of viral load to undetectable levels is one of several measures of antiviral treatment response; a sustained, undetectable viral load is an important goal of chronic hepatitis B treatment. The results of this three-year cohort were presented today at the 57th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD).

Parkinson’s Disease :: Boehringer Ingelheim’s pramipexole, mirapexin/sifrol to improve depressive and motivational symptoms

New data presented today from a meta-analysis* of nearly 1,300 Parkinson?s disease (PD) patients, indicate that pramipexole (Mirapexin?/Sifrol?) has a beneficial effect on depressive and motivational symptoms in PD.1 This confirms findings from previously published clinical trials,2,3,4 and is in addition to its established efficacy in controlling motor symptoms. These findings are of particular interest as mood symptoms in PD can affect up to 50 percent of the patient population.1,5 The data were presented at the 10th International Congress of Parkinson?s Disease and Movement Disorders (MDS) in Kyoto, Japan.

Hepatitis :: Glaxo eltrombopag improved platelet count in hepatitis C patients with thrombocytopenia

GlaxoSmithKline plc [NYSE:GSK, LSE:GSK] announced results from a global Phase II study of eltrombopag, an investigational non-peptide oral platelet growth factor. In this study of 74 hepatitis C patients with thrombocytopenia, (a condition where the blood has low platelet levels) more than 95% (p< 0.001) of patients treated with the highest dose of eltrombopag (75mg) had increased platelet counts. In addition, 71% - 91% of patients in all treatment groups were able to initiate antiviral therapy with pegylated interferon-α (IFN) and ribavirin, and 65% were able to be maintained on therapy.1 Full results from this Phase II study are being presented today at the 57th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD) in Boston, Massachusetts.

Back Pain :: Physical Therapy for the Lower Back – How to Prevent and Treat Lower Back Pain

Lower back pain is one of the most common causes of job-related disability and why some people miss work. It is also the second most common neurological ailment in the United States, second only to headache. In fact, approximately 80% of adults in Western countries have, at some point, experienced lower back pain.

Influenza :: Good medicines for flu, influenza in alternative medicines

“Friends, as the winters are coming, they are bringing influenza with them. So, be prepared to fight the disease and know about it,” Dr. Poonam Singhal. Influenza, also called grippe or flu, an acute contagious viral infection characterized by inflammation of the respiratory tract and by fever, chills, muscular pain, and prostration, with cough, cold, sneezings, intense frontal headache, pain and aches in joints, fever (100 deg. F to 105 deg. F), nausea, etc.

ADHD :: Lilly’s Strattera, atomoxetine effective in treating ADHD in children and adolescents

New data suggest that Strattera? (atomoxetine HCl) improved ADHD symptoms in children and adolescents who had both ADHD and a reading disorder, like dyslexia. Results were announced at a meeting of child and adolescent psychiatrists.