Cancer :: Antitumor compound blocks heat shock protein
Deguelin, a natural compound known to have antitumor properties, appears to disrupt the function of heat shock protein 90 (Hsp90), which cancer cells may need to grow.
Growth
Hearing Loss :: Gene responsible for common hearing loss identified for first time
A gene responsible for the single most common cause of hearing loss among white adults, otosclerosis, has been identified for the first time, a scientist told the annual conference of the European Society of Human Genetics in Nice, France. Melissa Thys, from the Department of Medical Genetics, University of Antwerp, Belgium, said that this finding may be a step towards new treatments for otosclerosis, which affects approximately one in 250 people.
Cancer :: CSHL scientists successfully target tumor microenvironment to stop cancer growth
Cold Spring Harbor Laboratory (CSHL) researchers led by Daniel Nolan and Assistant Professor Vivek Mittal have found that bone marrow (BM) derived endothelial progenitor cells (EPCs) play a critical role in the early stages of tumor progression and that eliminating EPCs stops cancer growth.
Bacteria :: Deprived bacteria grow up meaner
If the Listeria monocytogenes bacteria behind food poisoning are starved of oxygen, they are liable to turn really nasty according to research published today in the online journal BMC Microbiology. Limiting oxygen produces bacteria up to 100 times more invasive than similar bacteria grown with ample oxygen supplies.
Ovarian Cancer :: Hormone therapy offers new hope for ovarian cancer patients
Researchers at the University of Edinburgh have shown that hormone therapy can extend life in ovarian cancer patients, giving women a new alternative to chemotherapy.
Screening :: Screening approach leads to discovery of gene linked to breast cancer
Using a novel three-part screening process, scientists at Dana-Farber Cancer Institute have identified a gene that is made inappropriately in about a third of all breast cancers. The discovery, reached in collaboration with researchers at Brigham and Women?s Hospital (BWH) and the Broad Institute of Harvard and MIT, is reported in the June 15, 2007 issue of the journal Cell.
HIV :: Mucosal-surface immune function discoveries could boost vaccine research
In a finding that could have important implications for HIV vaccine research, new research at Weill Cornell Medical College illuminates the ways in which the body prevents its mucosal surfaces from being overwhelmed by bacteria.
Gene :: Clocking in and out of gene expression
A chemical signal acts as time clock in the expression of genes controlled by a master gene called a coactivator, said Baylor College of Medicine researchers in a report that appears in the journal Cell today.
Diabetes :: Cytokine resistance contributes to pathology of type 2 diabetes
In a study appearing this month in the Journal of Immunology, researchers at the University of Illinois describe how an impaired anti-inflammatory response plays a role in the pathology of type 2 diabetes.
Cancer :: Study could impact noninvasive treatment of cancer tumors
Ram Devireddy, assistant professor of mechanical engineering at LSU, recently co-authored an article with Todd Monroe, assistant professor of biological and agricultural engineering, investigating the complex effects of nanoparticles on cell freezing. The report was published in the prestigious journal Nanotechnology.