Breast Cancer :: Pathway links inflammation, angiogenesis and breast cancer

A well-known inflammatory protein spawns an enzyme that inactivates two tumor-suppressing genes, ultimately triggering production of new blood vessels to nourish breast cancer cells, researchers at the University of Texas M. D. Anderson Cancer Center report in the August edition of the journal Cell.

Aspirin :: Coated aspirin can still harm stomach

Some people take aspirin without ever having a problem with their stomach. Others develop low-grade stomach pain or get an ulcer. A few develop gastrointestinal bleeding severe enough to require a transfusion. But coated or buffered aspirin doesn?t do much to help, according to a four-page special report on aspirin in the August 2007 issue of the Harvard Heart Letter.

Marburg Disease :: UN helps Uganda respond to case of deadly Marburg disease

The UN is helping the Government of Uganda in outbreak response and containment activities following a confirmed case of Marburg virus disease, a rare but highly fatal haemorrhagic illness with epidemic potential, but there is at present no indication of a need to restrict travel or trade with the East African country.

Heartburn :: Cognitive impairment link found in older adults taking popular stomach acid medications

Long-term use of histamine2 receptor antagonists (H2A), one class of drugs that blocks stomach acid, may be associated with cognitive impairment in older African-American adults. According to an Indiana University School of Medicine and Regenstrief Institute study published in the August issue of the Journal of the American Geriatrics Society, the risk for showing signs of cognitive impairment is 2.5 times greater for patients using these medications long-term.

Anthrax :: Taming the anthrax threat

In the American government?s biodefense efforts, the potential for terrorists to cause a deadly anthrax outbreak remains a significant concern, six years after the letter attacks that shook the nation shortly after 9/11.

Gene :: Under magnetic force, nanoparticles may deliver gene therapy

After binding DNA segments to tiny iron-containing spheres called nanoparticles, researchers have used magnetic fields to direct the nanoparticles into arterial muscle cells, where the DNA could have a therapeutic effect. Although the research, done in cell cultures, is in early stages, it may represent a new method for delivering gene therapy to benefit blood vessels damaged by arterial disease.

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