Gene :: Researchers identify genetic mutation that may alter tumor cell proliferation

Researchers from Eli Lilly & Company and the Phoenix-based Translational Genomics Research Institute (TGen) today announced finding a novel recurring mutation of the gene AKT1 in breast, colorectal and ovarian cancers. The altered form of AKT1 appears to cause tumor cell proliferation and may play a role in making cells resistant to certain types of therapies. The findings are reported in an advance online publication (AOP) of the journal Nature.

Diet :: Common environmental chemicals in diet affect fetal ovarian development

Exposing a developing female sheep fetus to low doses of chemicals commonly present in the environment can disturb the development of the ovary, a scientist told the 23rd Annual Conference of the European Society of Human Reproduction and Embryology today (Wednesday, July 4). Dr. Paul Fowler, of the University of Aberdeen, Scotland, UK, said that this research would help to establish the importance of the effect of environmental chemicals for fertility.

Tuberculosis :: Neutrophils stand guard against tuberculosis infection

In the July 2 issue of the Journal of Clinical Investigation, Adrian Martineau, Robert Wilkinson, and colleagues from the Wellcome Trust Center for Research in Clinical Tropical Medicine in London report that the activity of white blood cells known as neutrophils is one reason why some individuals exposed to the infectious bacterium Mycobacterium tuberculosis resist developing evidence of tuberculosis (TB) infection for longer than their peers.

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