Kidney :: Molecular mechanism of common forms of kidney disease identified

Massachusetts General Hospital (MGH) researchers have identified a key mechanism underlying proteinuria – excess protein in the urine which signifies a breakdown in the kidney’s filtering process. They have discovered that a protein called dynamin is required for the function of a critical filtering structure called a podocyte and that a specific enzyme’s processing of dynamin will cause podocytes to break down, allowing protein to leak out of the bloodstream.

Mental Health :: Eleven more areas set to benefit from talking therapy projects, UK

New Mental Health Minister Ivan Lewis in his first major announcement, signalled the Government’s commitment to lead a radical change in the way mental health services are delivered. He today gave the go-ahead for eleven new projects which will allow people with anxiety and depression better access to psychological therapies.

Migraine :: Why women get more migraines than men

For every man with a migraine, three women are struck by the severe headaches that often come with nausea, sensitivity to light and sound, and aura. That means a staggering 18 to 25 percent of women suffer from migraines, making it one of the most common disabling conditions faced by women around the globe.

Multiple Sclerosis :: Betaferon delays disability progession after multiple sclerosis attack

Patients treated with Betaferon? (interferon beta-1b) shortly after their first clinical MS event or ?attack? showed a 40 percent lower risk of developing confirmed disability when compared to patients in whom treatment was delayed. The results ? which were fast-tracked and published in The Lancet today ? provide the first controlled evidence that delaying Betaferon? treatment has an effect on later accumulation of disability. No other MS therapy has demonstrated this effect in this early patient population.

Diabetes :: Takeda responds to the FDA advisory committee recommendation

Following a joint meeting of the US Food and Drug Administration Endocrinologic and Metabolic Drugs Advisory Committee and the Drug Safety and Risk Management Advisory Committee, Takeda Global Research & Development underscores its position that ACTOS (pioglitazone HCl) offers a proven safety profile regarding the risk of cardiovascular disease.

Liver Cancer :: Coffee may reduce liver cancer risk

A new study on the relationship between coffee drinking and the risk of hepatocellular carcinoma (HCC) confirmed that there is an inverse association between coffee consumption and liver cancer, although the reasons for this relationship are still unresolved. The results of this study appear in the August 2007 issue of Hepatology, the official journal of the American Association for the Study of Liver Diseases (AASLD).

HIV :: Abstinence from sex programs ineffective to cut HIV infection risk

In the developing world the contribution of the ?ABC? message (abstinence, be faithful, use a condom) remains unknown. Programmes that exclusively encourage abstinence from sex do not seem to affect the risk of HIV infection in high income countries, finds a review of the evidence in this week?s BMJ.

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