Obesity :: Possible link between obesity and viral infections

Experts don’t dispute the important role that diet and activity play in maintaining a healthy weight. But can poor eating habits and a less active lifestyle fully explain the prevalence of obesity in the United States today? That question has led some researchers to ask whether there might be other causes for this serious problem. In the October issue of Mayo Clinic Proceedings, researcher Richard Atkinson, M.D., asserts that there is a growing body of evidence demonstrating that viruses may play a role in causing obesity in humans.

Drug :: How does the antitumor drug get to the cell nucleus?

Platinum complexes such as the well-known cisplatin are powerful antitumor medications. They cross the cell membrane and reach the nucleus, where they attach to DNA and stop cell growth. But how does cisplatin get to the nucleus? Italian researchers have now proven that a copper transport protein may play a critical role. In the journal Angewandte Chemie, they present their hypothesis about the transport mechanism.

Folic Acid :: Folic acid linked to increased cancer rate

Two recent commentaries appearing in the November issue of Nutrition Reviews find that the introduction of flour fortified with folic acid into common foods was followed by an increase in colon cancer diagnoses in the U.S. and Canada. The two new review articles address these recent findings and provide an overview of the existing evidence on folic acid fortification and the associated policy issues.

HIV :: HIV-TB spreads in Africa, undermines control of world’s 2 deadliest infectious diseases

The largely unnoticed collision of the global epidemics of HIV and tuberculosis (TB) has exploded to create a deadly co-epidemic that is rapidly spreading in sub-Saharan Africa. However, health systems cannot adequately diagnose, treat, or contain the co-epidemic due to unanswered scientific and medical questions, according to a report issued today by The Forum for Collaborative HIV Research and amplified by experts from leading global health organizations.

Heart :: Gene, stem cell therapy only needs to be 50 percent effective to create a healthy heart

Heart disease is the leading cause of death in the United States and greatly affects the quality and length of life for individuals with specific forms of muscular dystrophy. Recent discoveries have demonstrated that gene and/or stem cell therapy could help a variety of organs in the body, but until now scientists have been unsure whether the heart could benefit from these treatments.

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