Stroke :: Two-Week Regimen Helps Stroke Survivors Regain Arm Control

In the largest, most comprehensive study of its kind to date, researchers supported by the National Institutes of Health (NIH) showed clinical improvements out to one year when stroke survivors who had lost function in one arm were given a unique, two-week rehabilitation regimen.

Macular Degeneration :: Laser Treatment Does Not Prevent Vision Loss for People with Early Age-Related Macular Degeneration

An extensive NIH-supported study has found that low-intensity laser treatment, thought to be possibly beneficial in slowing or preventing the loss of vision from age-related macular degeneration (AMD), is ineffective in preventing complications of AMD or loss of vision. This is the major conclusion of the Complications of Age-Related Macular Degeneration Prevention Trial (CAPT), a research study of more than 1,000 people that will be published in the November 2006 issue of the journal Ophthalmology. The study was supported by grants from the National Eye Institute (NEI) of the National Institutes of Health (NIH).

Arthritis :: Botox can treat Knee Pain

Mayo Clinic seeks adults who are age 40 or older and have knee pain that has not responded to medicines, exercise or physical therapy for a research study. The purpose of this research study is to find out what effects (good and bad) the botulinum toxin (Botox) has on patients with knee arthritis. Eligible participants will have been diagnosed with knee arthritis that can be confirmed by x-ray.

Cancer :: Harnessing the Measles Virus to Attack Cancer

Mayo Clinic Cancer Center has opened a new clinical study using a vaccine strain of the measles virus to attack recurrent glioblastoma multiforme, a largely untreatable brain tumor. This is the second of several pending molecular medicine studies in patients using measles to kill cancer.

Restless Legs Syndrome :: Boehringer Ingelheim’s pramipexole effective in RLS patients

New data presented today show patients taking pramipexole (Mirapexin?/ Sifrol?) can experience significant improvements in a broad range of symptoms associated with Restless Legs Syndrome (RLS).1 In an additional study presented today, pramipexole was also shown to be well tolerated in RLS patients affected by concomitant diseases, which are commonly experienced in this patient group.2 The results of the studies were presented at the 10th International Congress of Parkinson?s Disease and Movement Disorders (MDS) in Kyoto, Japan.

Baby Care :: Defective serotonin pathways in the brainstem may increase infants’ vulnerability – SIDS

New autopsy data provide the strongest evidence yet that sudden infant death syndrome (SIDS) is not a “mystery” disease but has a concrete biological basis. In the November 1 issue of JAMA, researchers at Children’s Hospital Boston document abnormalities in the brainstem — a part of the brain that regulates breathing, blood pressure, body heat, and arousal — in babies who died from SIDS. The term cot death is often used in the United Kingdom, and crib death in North America.

Breast Cancer :: Breast cancer gene offers promising target for drugs

Researchers at UT Southwestern Medical Center have for the first time described how multiple copies of a gene are responsible for metastases in early-stage breast cancer and poor prognosis for patients. In a study published in this week’s issue of the Proceedings of the National Academy of Sciences, the gene, called uPAR, offers a promising target for therapeutic drugs to stop or slow the progression of the disease and could serve as a screening tool for assessing which types of drugs a patient will respond to.

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