Endocrinology :: The more mutations the worse the disease in idiopathic hypogonadotropic hypogonadism

Idiopathic hypogonadotropic hypogonadism (IHH) is an inherited genetic disorder that results in impaired sexual development due to a deficiency in a sex hormone known as GnRH. Although individuals are thought to inherit IHH by having just one gene defect (in any one of a number of genes), not all the evidence supports this hypothesis, for example, not all family members with a given gene defect have the same symptoms.

Alternative Medicine :: 69% older Americans using complementary and alternative medicine

In spite of the high use of complementary and alternative medicine (CAM) among people age 50 or older, 69 percent of those who use CAM do not talk to their doctors about it, according to a new survey conducted by AARP and the National Center for Complementary and Alternative Medicine (NCCAM) at the National Institutes of Health. The survey examined conversations between patients and their physicians regarding CAM use.

Neurofibromatosis :: Tracing the pathways of neurofibromatosis

New research into the mechanisms of neurofibromatosis finds that flaws in the gene Nf1 can lead to a biochemical domino effect that results in tumors. The research, which appears in the January 10 issue of the Journal of Neuroscience, seeks to identify the biochemical pathway responsible for tumors in people with the genetic disorder. Researchers built their case based on evidence from dozens of painstaking experiments on genetically engineered fruit flies.

Schizophrenia :: Evidence Lacking to Support Many Off-label Uses of Atypical Antipsychotics

Some newer antipsychotic medications approved to treat schizophrenia and bipolar disorder are being prescribed to millions of Americans for depression, dementia, and other psychiatric disorders without strong evidence that such off-label uses are effective, according to a new analysis by the Department of Health & Human Services’ (HHS) Agency for Healthcare Research and Quality (AHRQ).

Fertility :: RCOG statement on the BBC Panorama programme IVF Undercover

The Royal College of Obstetricians and Gynaecologists (RCOG) promotes good practice in the field of reproductive medicine through its own guidelines, and supports those recently published by NICE. It provides formal subspecialist training programmes in reproductive medicine through which additional highly specialised training is received by specialist gynaecologists, who are expected to practice to the very highest standards in infertility provision.

Foot Pain :: Childhood Obesity Linked to Foot Pain

Doctors with the American College of Foot and Ankle Surgeons (ACFAS) say they’re noticing more and more overweight and obese children with foot and ankle pain in their examining rooms, mirroring a national epidemic of childhood obesity.

Gum Disease :: Gum disease linked to pancreatic cancer

Gum disease, tooth loss or periodontal disease, inflammation of the gums caused by bacterial infection that leads to tooth loss, was shown to be associated with increased risk of pancreatic cancer in two studies. In one study, all subjects were smokers, and in the other, no adjustment was made for smoking, a known risk factor for pancreatic cancer.

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