Preliminary findings indicate a heart failure medication used by adults, carvedilol, may not significantly improve heart failure outcomes for children and adolescents, according to an article in the Sept. 12 issue of JAMA.
UCSF scientists are reporting what they say is a significant improvement in the technique for genetically reprogramming mouse cells to their embryonic state, a process that transforms the cells, in essence, into embryonic stem cells.
An analysis of four studies involving more than 14,000 patients found that long-term use of the diabetes drug rosiglitazone (Avandia) increased the risk of heart attack by 42 percent and doubled the risk of heart failure, according to a new report from researchers at Wake Forest University School of Medicine and colleagues. There was no effect on death from cardiovascular causes.
Thanks to a $1.6 million grant from the Welch Foundation, a coalition of six Gulf Coast institutions is launching a new initiative to develop innovative computational and chemical techniques intended to speed the development of new drugs and molecular tools for biomedical science.
Takeda Pharmaceuticals North America, Inc. is aware of the review of ACTOS (pioglitazone HCl) data conducted by A. Michael Lincoff, M.D., and colleagues at the Cleveland Clinic, published in the Journal of the American Medical Association, which concluded that ACTOS is associated with a significantly lower risk of heart attack, stroke or death among a diverse population of 16,390 patients with diabetes versus control therapy.
An increase in high-grade prostate cancer among men taking the drug finasteride is likely caused by an increased detection of cancers, and not by the development of more high-grade cancers, according to two studies published online September 11 in the Journal of the National Cancer Institute.
A tailored virus destroys brain tumor stem cells that resist other therapies and cause lethal re-growth of cancer after surgery, a research team led by scientists at the University of Texas M. D. Anderson Cancer Center reports in the Sept. 18 edition of the Journal of the National Cancer Institute.
Research here shows that an obscure form of RNA, part of the protein-making machinery in all cells, might play an important role in human cancer. These ultraconserved non-coding RNAs (UCRs) have been considered ?junk? by some researchers, but a new report in the September issue of the journal Cancer Cell indicates that this may not be the case.
Prof. Ehud Assia, of Tel Aviv University?s Sackler School of Medicine is, quite simply, a rock star in the field of eye surgery. One of a small number of surgeons in the world who currently perform a complicated form of glaucoma surgery, Prof. Assia has developed a novel laser device that promises to revolutionize treatment of the disease.
The drug tadalafil appears to improve erectile function in men with spinal cord injuries, according to an article posted online today that will appear in the November 2007 print issue of Archives of Neurology, one of the JAMA/Archives journals.