Researchers at the University of Illinois at Chicago College of Pharmacy are attempting to discover how genes determine how well an antipsychotic medication works in adults and children and the side effects it will cause.
The Sea Urchin Genome Sequencing Project consortium, led by the Human Genome Sequencing Center at Baylor College of Medicine in Houston, announced today the decoding and analysis of the genome sequence of the sea urchin, Strongylocentrotus purpuratus.
Potentially blinding blood vessel growth in the cornea resulting from eye injury or even surgery can be reduced by more than 50 percent with a new manmade protein, researchers say.
Minorities account for 30 percent of the U.S. population, but only eight percent of the physician workforce, and experience less personal satisfaction during medical school than nonminority students, finds a Mayo Clinic study published in the November issue of Mayo Clinic Proceedings.
A new study by University of Arkansas economists shows a strong relationship between economic freedom and access to water. David Gay and Charles Britton, economics professors in the Sam M. Walton College of Business, and Richard Ford, professor of economics at the University of Arkansas at Little Rock, compared data from two important international indices and found that greater economic freedom leads to economic development, which in turn decreases the amount of poverty associated with a nation’s lack of access to water.
Health care professionals say a computerized emergency response system for public health laboratories developed in Nebraska is proving to be a valuable tool for other states and has the potential to impact public health systems worldwide.
Inhibiting a particular cancer-causing gene can enhance the cell-killing effects of radiation, a team of radiation oncologists and cancer biologists has found. Using a combination of zebrafish and antisense technology, they’ve shown that the drug flavopiridol works by blocking the activity of a gene, cyclin D1, which is overexpressed in about half of all breast cancers. Similar techniques in the future, the scientists say, may enable researchers to better gauge the effects of drugs.
With the help of tiny, transparent zebrafish embryos, researchers are hoping to prove that a microscopic nanoparticle can be part of a “new class of radioprotective agents” that help protect normal tissue from radiation damage just as well as standard drugs. They’ve shown that the nanoparticle, DF-1 — a soccer ball-shaped, hollow, carbon-based structure known as a fullerene — is as good as two antioxidant drugs and FDA-approved Amifostine in fending off radiation damage from normal tissue.
Scientists from King’s submitted a licence application yesterday (6 November) to the Human Fertilisation and Embryology Authority (HFEA) to allow them to fuse human cells with animal eggs. If granted, the licence will boost research into some of the most debilitating and untreatable neurological diseases.
Antiretroviral therapy can keep HIV infection in check and delay and ameliorate the symptoms of HIV/AIDS. However, the drugs do not manage to eradicate the virus completely; individuals have to stay on the drugs permanently. Preclinical studies in mice by Ekatarina Dadachova and colleagues (Albert Einstein College of Medicine) published in the international open-access journal PLoS Medicine now suggest a new strategy to locate and kill many if not all HIV-infected cells in the body.