Sticky proteins provide new insight into drug action
How drugs such as adrenalin do primarily one thing — in this case, increase the heart rate — now makes more sense to scientists.
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Osteoarthritis :: Mayo researchers note that stronger leg muscles can protect against knee osteoarthritis
Stronger quadriceps muscles in the legs can help protect against cartilage loss behind the kneecap, according to Mayo Clinic researchers presenting preliminary study data at the American College of Rheumatology Annual Meeting on Nov. 15.
To prevent terror attacks, strengthen airport screening of all travelers, not just suspects
The best way to prevent airborne terrorist attacks may be to improve the baseline security screening of all air travelers rather than identifying and screening high-risk passengers, according to new research by experts at MIT and Harvey Mudd College.
Immunity :: T for two – Scientists show how immune system chooses best way to fight infection
A new study has suggested a novel way of combating diseases related to the immune system, including cancer and autoimmune diseases such as type I diabetes and arthritis. The study, funded by the Wellcome Trust, appears online in the journal Nature.
Ankylosing Spondylitis :: Enbrel provides sustained clinical improvements for ankylosing spondylitis for up to 3 years
Amgen (NASDAQ: AMGN) announced patients with ankylosing spondylitis who received treatment with Enbrel (R) (etanercept) experienced sustained improvement in signs and symptoms, spinal mobility and physical function over 148 to 160 weeks of therapy, according to data from an ongoing open-label, multinational, phase 4 extension study presented at the American College of Rheumatology scientific meeting. These results are consistent with an ENBREL phase 3 clinical trial at 24 weeks.
Rheumatoid Arthritis :: Enbrel first biologic with up to 9 years rheumatoid arthritis safety
Amgen (NASDAQ: AMGN) announced Enbrel (R) (etanercept) is the first biologic with published data to show sustained improvements in multiple efficacy measures in rheumatoid arthritis patients completing up to nine years of therapy. Current data suggest Enbrel is both effective and safe in long-term RA use, and the new data, presented at the American College of Rheumatology scientific meeting, provide a degree of reassurance that unexpected safety concerns do not appear to develop after nine years of use.
Heart Disease :: Specific strategic plans ensure timely emergency care for heart attack patients
Hospitals that provide the most rapid emergency angioplasty have specific strategies to expedite the care of patients with heart attacks, researchers at Yale School of Medicine report in the November 13 New England Journal of Medicine.
Diabetes :: Diabetes drug may reduce cardiovascular risks
A drug commonly used to increase the body’s sensitivity to insulin may slow the progression of cardiovascular disease in patients with type 2 diabetes, according to a study at the University of Illinois at Chicago College of Medicine.
MRI :: Effectiveness of noninvasive whole-heart MRI
Researchers have long sought to find a reliable way to see inside the human heart without having to insert tubes, inject dyes or expose patients to potentially dangerous radiation. One possible solution is the whole-heart MRI, which provides 3-D images of the heart and its blood vessels without the risk of an invasive procedure.
Rett Syndrome :: New insight about the source of anxiety in Rett syndrome
A peptide known to play a role in anxiety is overly plentiful in a mouse model of the inherited neurological disorder Rett syndrome and appears to underlie the anxiety-like behavior in these mice, said researchers from Baylor College of Medicine in a report that appears online in the Proceedings of the National Academy of Sciences. The finding could provide a clue to treatment for this symptom.