ADHD :: Daytrana, methylphenidate transdermal system provides individualized ADHD symptom management

Shire plc (LSE: SHP, NASDAQ: SHPGY, TSX: SHQ) announced that its Attention Deficit Hyperactivity Disorder (ADHD) patch, DAYTRANA tm (methylphenidate transdermal system), has significant efficacy in reducing the symptoms of ADHD in children aged 6 to 12 years, even when the ADHD patch is taken off earlier than the recommended nine hours. The ability to remove the patch earlier than the recommended nine-hour wear time allows physicians the opportunity to manage the potential for late-day side effects, such as lack of appetite or difficulty sleeping. These phase IIIb clinical trial results were reported today at a major scientific and educational meeting of child and adolescent psychiatrists in San Diego, Calif.

ADHD :: Lisdexamfetamine dimesylate in ADHD phase 3 data presented

Shire plc (LSE: SHP, NASDAQ: SHPGY, TSX: SHQ) and its collaborative partner New River Pharmaceuticals Inc. (NASDAQ: NRPH) announced today that their investigational ADHD treatment, lisdexamfetamine dimesylate (also known as NRP104 or LDX), yielded a 60 percent improvement in the primary rating scale scores for symptoms of Attention-Deficit/Hyperactivity Disorder (ADHD) in children aged 6 to 12 years who received six months of treatment in an open-label phase III study. Results also demonstrated that at 6 months, 95 percent of children taking lisdexamfetamine dimesylate (NRP104/LDX) produced a “much improved” or “very much improved” rating on the Clinical Global Impressions ? Improvement score. These results were presented last weekend at a national meeting of child and adolescent psychiatrists.

Health :: Painful metaphors of workplace bullying

Workplace bullying negatively impacts employees’ physical and mental health, leading to higher company costs including increased employee illness, use of sick days, and medical costs, ultimately affecting productivity. Studies report that 25-30% of employees experience bullying and emotional abuse sometime during their work life.

ADHD :: Many adults with psychiatric disorders may also have undiagnosed ADHD

Shire plc (LSE: SHP, NASDAQ: SHPGY, TSX: SHQ) announced today that many adults with a depressive disorder, Bipolar Disorder (BPD), or an anxiety disorder may also have undiagnosed Attention-Deficit/Hyperactivity Disorder (ADHD), according to a longitudinal retrospective medical claims analysis presented today at a major medical meeting of child and adolescent psychiatrists.

Pregnancy :: Career women freezing their eggs until they find a right partner

Most women who freeze their eggs for later use to remove the pressure to find Mr Right, and to preserve their fertility would consider using them to become single mothers. A study of patients who have had their eggs frozen at an IVF clinic in New York suggests that 80 per cent would think about having them fertilised with donor sperm if they failed to find a suitable partner.

Flu :: Exaggerated expectation of flu, influenza vaccines

“We’ve got an exaggerated expectation of what vaccines can actually do,” said study author Dr. Tom Jefferson, coordinator of the Cochrane Vaccines Field in Rome, Italy. “I’m hoping American and European taxpayers will be alerted and will start asking questions.”

Polio :: Poliomyelitis in Kenya

One case of wild poliovirus type-1, due to an importation of virus from neighbouring Somalia, has been reported from a Somali refugee camp in northeastern Kenya. The 3-year old girl (who was born in Kenya and had not traveled to Somalia) had onset of paralysis on 17 September 2006. The case is in the district of Garissa in North Eastern Province bordering Somalia, where an outbreak of poliomyelitis has resulted in 216 cases to date since July 2005. Genetic sequencing indicates a virus of Nigerian origin, imported from Kismayo, Somalia; however, it is not possible to determine how long the virus has been circulating in Kenya. A joint national/international rapid response team is conducting a detailed clinical and epidemiological investigation.

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