Breast Cancer :: New therapeutic target in breast cancer fight

Researchers at the McGill Cancer Centre revealed they had managed to delay or completely suppress the onset of one particular strain of the breast cancer disease in lab mice.

Michel Tremblay and colleagues report that deletion of the phosphatase PTP1B delays the development of mammary tumors in mice expressing an oncogenic form of ErbB2. They also observe less progression to metastatic cancer of the lung, suggesting that PTP1B might be a new target in the treatment of breast cancer.

Every woman is at risk for breast cancer. If she lives to be 85, there is a one out of nine chance that she will develop the condition sometime during her life. As a woman ages, her risk of developing breast cancer rises dramatically regardless of her family history. The breast cancer risk of a 25-year-old woman is only one out of 19,608; by age 45, it is one in 93. In fact, less than 5% of cases are discovered before age 35 and the majority of all breast cancers are found in women over age 50.


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