Obesity :: Mind over matter – SH2B1 in the brain regulates obesity

Obesity is one of the main risk factors for developing type II diabetes. Previous studies have shown that mice lacking a protein known as SH2B1 throughout their body are obese and develop diabetes. However, a new study now shows that replacing SH2B1 only in the brain of these mice rescues them from obesity, indicating that SH2B1 in the brain might be a new target for the development of treatments for obesity and type II diabetes.

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