Brain :: Vanderbilt nets brain gene research center

Neuroscientists at Vanderbilt University are stepping into the national limelight with the establishment of a Silvio O. Conte Center for Neuroscience Research. The new center, funded by a $10 million grant from the National Institute of Mental Health (NIMH), will support interdisciplinary studies aimed at understanding the gene networks that control serotonin systems in the brain.

Gene :: Genes may hold the keys to how humans learn

New research is giving scientists fresh insights into how genetics are a prime factor in how we learn. Michael Frank, an assistant professor of psychology and director of the Laboratory for Neural Computation and Cognition at The University of Arizona, headed a team whose results are reported in the Oct. 1 issue of Early Edition, an online site hosted by the Proceedings of the National Academy of Sciences.

West Nile Virus :: Humans MIFfed by West Nile Virus

Infection with West Nile Virus (WNV) can cause lethal encephalitis and there are currently no vaccines or specific therapeutics for use in humans. However, data generated by Erol Fikrig and colleagues at Yale University School of Medicine has provided evidence that the proinflammatory soluble factor MIF might provide a target for developing therapeutics to treat WNV encephalitis.

Smoking :: New study reveals mechanism behind nicotine dependency

The new study reveals that, in rats, chronic nicotine use recruits a major brain stress system, the extrahypothalamic corticotropin releasing factor (CRF) system, which contributes to continued tobacco use by exacerbating anxiety and craving upon withdrawal. The researchers found that administering a compound that blocked the receptors involved in this stress system alleviated withdrawal symptoms.

Diabetes :: New study uncovers potential role of leptin in diabetes

A new Joslin-led study has shown that leptin, a hormone known mainly for regulating appetite control and energy metabolism, plays a major role in islet cell growth and insulin secretion. This finding opens up new avenues for studying leptin and its role in islet cell biology, which may lead to new treatments for diabetes.

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