Brain Tumors :: Newly identified biomarker detects and regulates spread of brain tumors

Researchers have identified a novel biomarker for brain tumors and have uncovered a potential role the marker may play when the tumor spreads or comes back after treatment. The biomarker, a protein known as “soluble attractin,” is normally absent in the central nervous system and is undetectable in cerebral spinal fluid unless malignant astrocytomas are present in the CNS. This newfound ability to identify biomarkers for malignant astrocytomas means physicians will have a minimally invasive method to track the success of treatments.

Cancer :: Firefighters face increased risk for certain cancers

University of Cincinnati (UC) environmental health researchers have determined that firefighters are significantly more likely to develop four different types of cancer than workers in other fields. Their findings suggest that the protective equipment firefighters have used in the past didn’t do a good job in protecting them against cancer-causing agents they encounter in their profession, the researchers say.

Stem Cell :: Cure for blindness – stem cell transplant in eyes – UK

A team of international researchers has transferred eye tissue from newborn to adult mice. It lets the blind adults detect light. The scientists say it challenges conventional wisdom on stem cells, because the successful cells had already stopped dividing before they were transferred.

Depression :: New depression model advances disease frontiers – CAMH

For over 30 years, scientists believed that monoamines are low in the brain during major depressive episodes. However, no one ever found a convincing explanation for monoamine loss. Dr. Jeffrey Meyer and colleagues discovered that higher levels of MAO-A is the primary process that lowers monoamine levels. Having more MAO-A leads to greater breakdown of chemicals like serotonin. Based on these results, and work from previous publications, Dr. Meyer developed an advanced monoamine model of depression.

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