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Botulism :: Molecular basis of botulism toxin’s deadly activity

Scientists at the Scripps Research Institute, the University of Wisconsin School of Medicine and Public Health, and the Howard Hughes Medical Institute have revealed in atomic detail how the toxins that cause botulism target and bind to nerve cells. This new understanding could ultimately lead to new ways for treating botulism, as well as to improved therapies for nervous system diseases such as dystonias, cerebral palsy and multiple sclerosis.

Eating :: Study finds gender differences related to eating and body image

Researchers have discovered a subtle new difference between men and women — this one occurring in the realm of eating.

Cancer :: Boost for new cancer therapies, blocking Polo kinase

Scientists have revealed the critical role a key enzyme plays in helping cells divide in what could prove an important breakthrough for new cancer therapies.

Healthcare :: New resuscitation guidelines may be saving lives in King County

Survival from out-of-hospital cardiac arrest is at an all-time high in King County, and a new method of resuscitation used by emergency medical responders in King County may be the reason. Since the protocol was adopted in 2005, survival rates jumped to 46% from 33% for the period of 2002 through 2004.

Education :: SC orders desealing of school in East Delhi, India

The Supreme Court today allowed the desealing of a school in East Delhi which was sealed by the Municipal Corporation of Delhi as it was operating on encroached land.

Lead :: Pros and cons of therapy for lead exposure

Lead chelation therapy can lessen learning and behavioral problems due to lead exposure, but the therapy adversely affected rats with no lead in their systems, a Cornell study shows. The finding has implications for the treatment of autistic children.

Injury :: Feet, rather than fists, the most dangerous bodily weapon to use in assaults

Feet, rather than fists, are the most dangerous bodily weapon available, reveals research on violent assaults, published in the journal Injury Prevention. The researchers base their findings on an assessment of nearly 25,000 people treated in emergency care in and around Cardiff, Wales between 1999 and 2005. All had sustained injuries during acts of violence.

Botulinum :: Seeing a neurotoxin’s deadly grip

Two Howard Hughes Medical Institute (HHMI) research teams working independently have discovered new information about how the botulinum neurotoxin shuts down neurons with deadly efficiency. By providing detailed views of the toxin plugged into its neuronal receptor, the new studies could aid efforts to engineer specialized versions of the powerful neurotoxin that is used to treat a wide array of medical problems.

Botulinum :: How botulinum toxin attaches to nerve cells – explained

A group of researchers, funded in part through two of NIAID’s Regional Centers of Excellence for Biodefense and Emerging Infectious Diseases, has provided a rare atomic glimpse of the initial step one of botulinu’s toxins takes to gain entry into human neurons. In an advanced online publication of the journal Nature, the scientists show structurally how botulinum neurotoxin B (one of seven toxins the bacterium produces) recognizes receptors on the surface of human neurons.

HIV :: Role of Nutrition in Health Care for People with HIV/AIDS

The American Dietetic Association commends Congress for passing a three-year reauthorization of the Ryan White CARE Act, the largest federal program specifically for people with HIV and AIDS, with new attention to the unique dietary needs of patients.