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Breast Cancer :: Preoperative chemotherapy is a safe option for women with early stage operable breast cancer

Chemotherapy is frequently given to women with breast cancer after surgery to remove the main bulk of the tumor. A new Cochrane Systematic Review of existing data shows, however, that using chemotherapy to reduce the size of tumors before surgery does not compromise survival rates and enables women to retain better self-image and overall health because of the reduced impact of the surgery.

Lung Cancer :: Intravenous nanoparticle gene therapy shows activity in stage IV lung cancer

A cancer-suppressing gene has been successfully delivered into the tumors of stage four lung cancer patients via an intravenously administered lipid nanoparticle in a phase I clinical trial at the University of Texas M. D. Anderson Cancer Center. The gene, FUS1, also was found to be active in the metastatic nonsmall cell lung cancer tumors.

Diabetes :: Abbott announces FDA clearance, launch of new FreeStyle Lite blood glucose monitor

Abbott Diabetes Care announced the launch of its FreeStyle Lite? blood glucose monitoring system for people with diabetes after receiving a 510(k) clearance from the U.S. Food and Drug Administration.

Paget’s Disease :: Reclast receives US approval as a treatment for patients with Paget’s disease of bone

Reclast? (zoledronic acid) has received US regulatory approval as the first new treatment in nearly a decade for patients with a bone condition known as Paget’s disease, estimated to affect about one million people in the US alone.

Lung :: Breathing for better lung health

While working to find novel ways to treat the life-threatening disease of cystic fibrosis, researchers at the University of North Carolina have discovered that the rhythmic motion of the lungs during normal breathing is a critical regulator of the clearance of bacteria and other noxious materials.

Crohn’s Disease :: Scientists find major susceptibility gene for Crohn’s disease

A consortium of Canadian and American researchers report in Nature Genetics the results from a search of the entire human genome for genetic risk factors leading to the development of Crohn’s disease.

Healthcare :: Treatment costs fall and quality improves when patients use self-treatment tools

Encouraging patients to become involved in providing their own care can reduce the cost and improve the quality of long-term medical treatment, say researchers from Massachusetts General Hospital and Massachusetts Institute of Technology in PLoS Medicine this week.

Imaging :: Bioluminescence at the service of a novel cerebral imaging technique

CNRS scientists in collaboration have developed a new technique for the in vivo imaging of neuronal function using bioluminescence, based on a GFP-aequorin fusion protein.

Crohn’s Disease :: Scientists find new genes for Crohn’s disease

Just a few months after their landmark article in Science magazine reporting the discovery of strong links between variations in a gene that codes for a cellular receptor involved in controlling inflammation and Crohn’s disease, a consortium of U.S. and Canadian researchers is reporting in today’s online issue of Nature Genetics that they have discovered several more genetic variations that are strongly linked to an increased risk for the disease.

Skin Cancer :: Antigen-cloning technique may boost skin cancer vaccine

In recent years, researchers have worked to develop a number of vaccines to help the immune system fight tumors. Cancer vaccines are not intended to prevent cancer; rather, they are used to boost immune responses to preexisting tumors.