Prostate Cancer :: Scientists design a PSA-activated protoxin that kills prostate cancer

Scientists have found a way of using a protein made by prostate cancer to target and kill the cancer cells themselves. In preliminary studies the new therapy affected only the prostate, without causing damage to other healthy tissues, and now it is being tested in a phase I clinical trial, according to research presented at the 18th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics in Prague on Friday.

Health :: Food Safety Consortium Summarizes Year’s Work

Multiple research projects across three cooperating universities are demonstrating progress that is enabling American producers, processors and consumers to maintain a safe food supply. The Food Safety Consortium summarized that work in its recently completed annual report for the 2005-06 fiscal year.

Ears :: Study shows most ear infections host both bacteria and viruses

Ear infections are among the most common diseases seen in pediatric practice. They have generally been considered bacterial diseases and are therefore usually treated with antibiotics. New research, published in the Dec. 15 issue of Clinical Infectious Diseases and currently available online, provides evidence that viruses are found in a great many ear infection cases and may complicate treatment.

Health :: Green plants share bacterial toxin

A toxin that can make bacterial infections turn deadly is also found in higher plants, researchers at UC Davis, the Marine Biology Laboratory at Woods Hole, Mass. and the University of Nebraska have found. Lipid A, the core of endotoxin, is located in the chloroplasts, structures that carry out photosynthesis within plant cells.

Health :: MRSA toxin acquitted – Study clears suspected key to severe bacterial illness

Researchers who thought they had identified the bacterial perpetrator of the often severe disease caused by community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) had better keep looking: Scientists at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, have exonerated a toxin widely thought to be the guilty party.

Gene :: Novel experiment documents evolution of genome in near-real time

UCSD bioengineers report in the November issue of Nature Genetics rapid evolutionary changes in a bacterial genome, observed in near-real time over a few days. Scientists have previously published static “snapshots” of the genome sequences of more than 100 bacterial species, but this new report shows how these genomes are moving targets.

Bacterial Vaginosis :: FDA Approves First Generic Metronidazole

The Food and Drug Administration approved the first generic version of MetroGel-Vaginal (metronidazole vaginal gel), a treatment for bacterial vaginosis. The approval is an important step in the agency’s effort to increase the availability of lower-cost generic medications.

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