Antibiotic :: GSK & Anacor Pharmaceuticals form alliance to develop systemic antivirals and antibiotics

GlaxoSmithKline and Anacor Pharmaceuticals announced that they have entered into a worldwide strategic alliance for the discovery, development and commercialisation of novel medicines for viral and bacterial diseases. The collaboration provides GlaxoSmithKline access to Anacor’s proprietary boron-based chemistry for use against selected targets.

Liver :: Mixing large doses of both acetaminophen painkiller and caffeine may increase risk of liver damage

Consuming large amounts of caffeine while taking acetaminophen, one of the most widely used painkillers in the United States, could potentially cause liver damage, according to a preliminary laboratory study reported in the Oct. 15 print issue of ACS’ Chemical Research in Toxicology, a monthly journal.

Health :: Pathway to cell death redefined in landmark study

A new study led by investigators from the University of Pittsburgh School of Medicine demonstrates that the process of necrosis, long thought to be a chaotic, irreversible pathway to cell death, may actually be triggered as part of a regulated response to stress by a powerful protein, SRP-6, that can potentially halt necrosis in its path.

Genetic :: Scientists Identify Cause of Job’s Syndrome

The rare immunodeficiency disorder known as Job’s syndrome is caused by a specific genetic mutation that both overstimulates and understimulates the human immune system, leading to harmful bacterial and fungal infections and the physical features characteristic of the syndrome, according to two independent groups of scientists, one from the National Institutes of Health (NIH) and the other from the Tokyo Medical and Dental University.

DNA :: Scientists reveal DNA-enzyme interaction with first ever real time footage

For the first time scientists have been able to film, in real time, the nanoscale interaction of an enzyme and a DNA strand from an attacking virus. Researchers from the University of Cambridge have used a revolutionary Scanning Atomic Force Microscope in Japan to produce amazing footage of a protective enzyme unravelling the DNA of a virus trying to infect a bacterial host.