In this retrospective cohort study that included 852 primary care physicians in Quebec, international medical graduates, physicians with high practice volumes and those who were in practice longer were more likely to prescribe antibiotics inappropriately.
GlaxoSmithKline and Anacor Pharmaceuticals announced that they have entered into a worldwide strategic alliance for the discovery, development and commercialisation of novel medicines for viral and bacterial diseases. The collaboration provides GlaxoSmithKline access to Anacor’s proprietary boron-based chemistry for use against selected targets.
A new University of Melbourne study has found that exclusive breastfeeding of babies with a family history of allergies increases their risk of developing asthma, eczema or food allergies in the long term.
Consuming large amounts of caffeine while taking acetaminophen, one of the most widely used painkillers in the United States, could potentially cause liver damage, according to a preliminary laboratory study reported in the Oct. 15 print issue of ACS’ Chemical Research in Toxicology, a monthly journal.
By better understanding how antimicrobials bind and thereby get inactivated in the mucus of air passages, researchers at the University of Illinois may have found a way to help cystic fibrosis patients fight off deadly infections.
The production of melanin gives us sunburns, but it also helps invertebrate animals to encapsulate attacking fungi and parasites. Uppsala University researchers, in collaboration with Korean and Thai colleagues, can now show that melanin also protects against bacterial infections, at least in crayfish.
A new study led by investigators from the University of Pittsburgh School of Medicine demonstrates that the process of necrosis, long thought to be a chaotic, irreversible pathway to cell death, may actually be triggered as part of a regulated response to stress by a powerful protein, SRP-6, that can potentially halt necrosis in its path.
The rare immunodeficiency disorder known as Job’s syndrome is caused by a specific genetic mutation that both overstimulates and understimulates the human immune system, leading to harmful bacterial and fungal infections and the physical features characteristic of the syndrome, according to two independent groups of scientists, one from the National Institutes of Health (NIH) and the other from the Tokyo Medical and Dental University.
The U.S. Food and Drug Administration has cleared for marketing the first rapid test to detect bacterial contamination in blood platelets prior to transfusion.
For the first time scientists have been able to film, in real time, the nanoscale interaction of an enzyme and a DNA strand from an attacking virus. Researchers from the University of Cambridge have used a revolutionary Scanning Atomic Force Microscope in Japan to produce amazing footage of a protective enzyme unravelling the DNA of a virus trying to infect a bacterial host.