Cholesterol :: Statin therapy associated with regression of coronary atherosclerosis with key lipid level changes

An analysis of data from four clinical trials suggests that statin therapy is associated with regression of coronary atherosclerosis when low-density lipoprotein cholesterol (LDL-C or “bad” cholesterol) is substantially reduced and high-density lipoprotein cholesterol (HDL-C or “good” cholesterol) is increased, but it remains to be determined whether this degree of atherosclerosis regression will translate to meaningful reductions in cardiovascular events, according to a study published in the Feb. 7 issue of JAMA.

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