Alzheimer’s Disease :: New gene uncovered for late-onset Alzheimer’s
An international team of researchers, led by Columbia University Medical Center, Boston University School of Medicine and the University of Toronto, has uncovered a major new gene — SORL1 — implicated in late-onset Alzheimer’s disease. Replicated in four distinct ethnic groups, SORL1 is only the second genetic variant for late-onset Alzheimer’s, the type of Alzheimer’s found in 90 percent of people with this devastating disease. ApoE4, the first, was identified in 1993.