A new study suggests that ovarian cancer cells form by hijacking a developmental genetic process normally used to form fallopian tubes. Scientists at the Georgia Institute of Technology and the Ovarian Cancer Institute discovered that the protein, PAX8, is involved in the development of fallopian tubes and is present in ovarian cancer cells, but not in normal ovarian tissue.
Joslin researchers discover a surprising culprit in the search for causes of diabetic birth defects. protein makes it possible for high blood glucose to enter embryonic cells.
Errors in stem cell division can give rise to tumours. By studying stem cells in the fruit fly, scientists at the Institute for Research in Biomedicine (IRB Barcelona) have identified one of the mechanisms that govern how these cells divide.
Mayo Clinic Cancer Center has opened a new Phase I clinical trial testing an engineered measles virus against multiple myeloma, a cancer of the bone marrow that currently has no cure.
In a move that could dramatically increase the nation’s supply of stem cells for transplantation, the Health Resources and Services Administration (HRSA), part of the U. S. Department of Health and Human Services, recently awarded a $9 million grant to the cord blood bank at The University of Texas M. D. Anderson Cancer Center.
New research has examined the usefulness of bone marrow stem cells for treating male infertility, with promising results. The related report by Lue et al, “Fate of bone marrow stem cells transplanted into the testis: potential implication for men with testicular failure,” appears in the March issue of The American Journal of Pathology.
In clinical studies for the lead indication of multiple sclerosis (MS), Revimmune improves function in most patients and stops progression in over 90 percent of cases refractory to standard therapies.
Researchers at Mount Sinai School of Medicine have just developed an advanced imaging technique to capture the movement of the microdomains of leukocytes or white blood cells.
Mayo Clinic researchers have safely transplanted cardiac preprogrammed embryonic stem cells into diseased hearts of mice successfully regenerating infarcted heart muscle without precipitating the growth of a cancerous tumor — which, so far, has impeded successful translation into practice of embryonic stem cell research.
MIT researchers have developed a technique to encourage the survival and growth of adult stem cells, a step that could help realize the therapeutic potential of such cells.