A combination of two drugs can selectively block pain-sensing neurons in rats without impairing movement or other sensations such as touch, according to a new study by National Institutes of Health-supported investigators. The finding suggests an improved way to treat pain from childbirth and surgical procedures. It may also lead to new treatments to help the millions of Americans who suffer from chronic pain.
The first reported findings from an international, Phase 3 study showed that more than two-thirds of patients with moderate to severe plaque psoriasis receiving two doses of ustekinumab (CNTO 1275) achieved at least a 75 percent reduction in psoriasis at week 12, the primary endpoint of the study, as measured by the Psoriasis Area and Severity Index (PASI 75).
A test to detect the very early stages of cancer could one day result from new research by Cardiff University scientists. A team at the University’s School of Medicine has just published a study on telomeres – small structures at the end of human chromosomes which can play a crucial part in the onset of cancer.
Flu vaccine delivered through painless microneedles in patches applied to the skin could soon be an alternative to delivery through hypodermic needles, according to researchers at Emory University and the Georgia Institute of Technology. Using new grants from the National Institutes of Health totaling approximately $11.5 million over five years, researchers from the two institutions plan to develop a new vaccine product using the microscopic needles.
According to a study carried out at the Department of Experimental Sciences of the University of Granada immigrant teenagers eat better than Spanish teenagers. For this reason, immigrant teenagers have a lower probability of suffering from obesity, diabetes and other cardiovascular diseases caused by bad eating habits.
Immune system cells recruited by cancers to help them grow and spread could be ‘re-educated’ to attack the tumours instead of aiding them, Cancer Research UK scientists announced at the National Cancer Research Institute (NCRI) Conference in Birmingham.
Specialised bath products to relieve the symptoms of allergic (atopic) eczema are of “questionable” value, says the Drug and Therapeutics Bulletin (DTB). The NHS forks out more than £16 million a year on bath emollients, equivalent to almost 40% of the total cost of eczema treatments prescribed for pre-school children, says DTB.
Among Medicare patients, men are about 2-3 times more likely than women to receive an implantable cardioverter-defibrillator for the prevention of sudden cardiac death, according to a study in the October 3 issue of JAMA.
A new University of Melbourne study has found that exclusive breastfeeding of babies with a family history of allergies increases their risk of developing asthma, eczema or food allergies in the long term.
A summary of evidence on the diagnosis and treatment of low-back pain has prompted the American Pain Society (ASP) and the American College of Physicians (ACP) to issue a new treatment guideline. The guideline is based on a thorough analysis of published research conducted by investigators at the Oregon Evidence-Based Practice Center at Oregon Health & Science University.