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Pregnancy :: Smoking, Nicotine and Pregnancy SNAP – patches and stop

1050 pregnant women are being recruited for the most extensive trial of its kind to establish the effect of using nicotine patches during pregnancy. The ?1.3m clinical trial ? Smoking, Nicotine and Pregnancy (SNAP) trial ? will investigate whether nicotine replacement therapy (NRT) is safe, effective and cost-effective for mums-to-be who want to give up smoking. It will also study the effect on the behaviour and development of the child.

Skin :: Skin rash actually signifies better outcomes for pancreatic and lung cancer patients

The appearance of a rash in cancer patients treated with erlotinib (Tarceva) is strongly associated with longer survival, according to researchers from the drug?s developer, OSI Pharmaceuticals, Inc.

Erectile Dysfunction :: POM Wonderful 100% Pomegranate Juice may improve erectile dysfunction

According to a pilot study released in the International Journal of Impotence Research (http://www.nature.com/ijir), POM Wonderful 100% Pomegranate Juice was found to have beneficial effects on erectile dysfunction (ED), a disorder that affects 1 in 10 men worldwide and 10 to 30 million men in the United States alone.

Depression :: Suicide attempts decline after depression treatment

In a study of more than 100,000 patients treated for depression, suicide attempts declined during the first month of treatment?whether that treatment consisted of medication, psychotherapy, or both.

Diabetes :: Saxagliptin with metformin improves glycemic control in type 2 diabetes patients

Saxagliptin, an inhibitor of dipeptidyl-peptidase-4 (DPP-4) in development by Bristol-Myers Squibb Company (NYSE: BMY) and AstraZeneca (NYSE: AZN), in combination with metformin, exhibited a statistically significant improvement in glycemic control in subjects with Type 2 diabetes compared to metformin alone through 24 weeks of treatment.

Constipation :: Chronic constipation study offers relief to all sufferers

A clinical trial including 50 medical centers and 304 patients has confirmed that polyethylene (PEG) laxative is safe for patients suffering from chronic constipation. The study, published in The American Journal of Gastroenterology, indicates that even elderly patients can use the drug safely for up to six months.

ADHD :: Shire receives FDA approvable letter for INTUNIV, a nonstimulant ADHD treatment

Shire plc (LSE: SHP, NASDAQ: SHPGY, TSX: SHQ) announced today that it has received an approvable letter from the U.S. Food and Drug Administration (FDA) for INTUNIV (guanfacine) extended release tablets (previously referred to as SPD503), a nonstimulant selective alpha-2A-receptor agonist that has been studied in children and adolescents with Attention-Deficit/Hyperactivity Disorder (ADHD).

Heart :: Stem cells to repair damaged heart muscle

In the first trial of its kind in the world, 60 patients who have recently suffered a major heart attack will be injected with selected stem cells from their own bone marrow during routine coronary bypass surgery.

Menopause :: Estrogen protects heart in young menopause women

Wyeth Pharmaceuticals, a division of Wyeth (NYSE:WYE), provides comment on the Women?s Health Initiative (WHI) Coronary Artery Calcium Study published in The New England Journal of Medicine (NEJM).

Malaria :: Effective treatment for malaria control during pregnancy in Africa

A review of previous studies indicates that two doses of a malaria preventive therapy during pregnancy provides substantial benefit to HIV-negative women in Africa, with more frequent dosing apparently necessary for HIV-positive women, according to an article in the June 20 issue of JAMA.